Results 91 to 100 of about 42,922 (196)

Microinvasive carcinoma of the cervix [PDF]

, 2004
BACKGROUND: Superficially invasive neoplasias of the uterine cervix are a matter of controversy in terms of their definition, prognostic factors and selection of treatment to minimize the risk of recurrences.
Mandić Aljoša, Mastilović Katarina, Ninčić Dejan P., Vujkov Tamara, Žikić Dragan 1, Živaljević Milica   +5 more
core   +1 more source

Why not vaginal?—Nationwide trends and surgical outcomes in low‐risk hysterectomies: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 5, Page 958-967, May 2025.
This study shows a decline in vaginal hysterectomies in Sweden 2014–2023 among patients with prerequisites for vaginal surgery. Our results support the vaginal route for low‐risk hysterectomies, both considering surgical outcomes and costs. Abstract Introduction The rate of vaginal hysterectomies is declining globally.
Johanna Wagenius, Sophia Ehrström, Karin Källén, Jan Baekelandt, Andrea Stuart   +4 more
wiley   +1 more source

Human Papilloma Virus genotypes in Type III cervical intraepithelial neoplasia. Cuenca–Ecuador, 2013-2017

Kasmera, 2019
Cervical cancer is one of the most common cancers in female population worldwide in underdeveloped countries, and in Ecuador it stands out in second place. This research focuses on HPV-genotype description in type III-intraepithelial neoplasms. The study
Patricio Santiago Tigre Sinchi, Zoila Katherine Salazar Torres, Lizette Espinosa Martin, Karla Alexandra Aspiazu Hinostroza, Hermel Medardo Espinosa, Freddy Rosendo Cárdena Heredia   +5 more
doaj   +1 more source

NOX Family: Regulators of Reactive Oxygen Species Balance in Tumor Cells

The FASEB Journal, Volume 39, Issue 8, 30 April 2025.
The NOX family regulates ROS production, influencing tumor proliferation, invasion, and angiogenesis. NOX2 and NOX4 modulate immune cell function in the tumor microenvironment, promoting immune escape. Targeting NOX enzymes with inhibitors or gene therapy offers potential therapeutic strategies to disrupt tumor progression and enhance antitumor ...
Bin Xiong, Yang Zhang, Siyi Liu, Shan Liao, Zihua Zhou, Qian He, Yanhong Zhou   +6 more
wiley   +1 more source

Identification of a Proliferation Gene Cluster Associated with HPV E6/E7 Expression Level and Viral DNA Load in Invasive Cervical Carcinoma [PDF]

Oncogene vol 24, p 7094-7104 (2005), 2005
Specific HPV DNA sequences are associated with more than 90% of invasive carcinomas of the uterine cervix. Viral E6 and E7 oncogenes are key mediators in cell transformation by disrupting TP53 and RB pathways. To investigate molecular mechanisms involved in the progression of invasive cervical carcinoma, we performed a gene expression study on cases ...
arxiv  

P16INK4A EXPRESSION AS A POTENTIAL PROGNOSTIC MARKER IN CERVICAL PRECANCEROUS AND CANCEROUS LESIONS IN MOROCCO [PDF]

, 2015
Introduction :The overexpression of p16INK4a is considered to be strong and consistent in HPV-induced cancers. The objective of this study was to investigate the presence of HPV DNA in cervical biopsies, and to study the overexpression of p16INK4a as a ...
Elgnaoui, Nadia, Fechtali, Taoufiq, Zouheir, Yassine   +2 more
core   +3 more sources

The Critical Role of Inhibitor of Differentiation 4 in Breast Cancer: From Mammary Gland Development to Tumor Progression

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Inhibitor of differentiation 4 (ID4) is a highly conserved DNA‐binding inhibitory protein of mammals, and its main role is to bind basic helix–loop–helix (b‐HLH) so that it loses its DNA‐binding activity, which in turn regulates the transcription of key genes, regulating cell differentiation and proliferation as the physiological function ...
Yuhang Song, Panshi Zhang, Sudhanshu Bhushan, Xinhong Wu, Hongmei Zheng, Yalong Yang   +5 more
wiley   +1 more source

Rates of unanticipated premalignant and malignant lesions at the time of hysterectomy performed for pelvic organ prolapse in an underscreened populationAJOG MFM at a Glance

AJOG Global Reports, 2023
BACKGROUND: The rate of unanticipated premalignant or malignant pathology at the time of hysterectomy performed for pelvic organ prolapse has been previously reported to be 0.2%.
Syem Barakzai, MD, Emma Koltun-Baker, BS, Samuel J.F. Melville, BS, Enanyeli Rangel, MD, Molly Dahl, MD, Christina E. Dancz, MD, MPH   +5 more
doaj  

The correlation between histopathological and ultrasound findings regarding Cesarean section scars – A three-year survey study [PDF]

, 2019
The cesarean operation represents a major surgery, with a higher risk of postoperative complications and longer postoperative recovery than vaginal delivery. Due to the increasing frequency of cesarean sections, the ultrasound imaging of the uterine scar
Bacalbașa, Nicolae, Bălălău, Cristian, Bălălău, Oana D., Dumitru, Vasile A., Ghinghină, Octav, Gălățeanu, Bianca, Negrei, Carolina, Pleș, Liana, Răduță, Cristina, Stănescu, Anca D.   +9 more
core   +1 more source

Routine 36‐week scan: diagnosis of fetal abnormalities

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 427-435, April 2025.
ABSTRACT Objectives To investigate further the incidence and types of fetal abnormality identified at a routine 36‐week ultrasound examination, which had not been diagnosed in previous scans at 20 weeks and 12 weeks' gestation, and to report the fetal abnormalities that are diagnosed only postnatally.
A. Syngelaki, R. Mitsigiorgi, J. Goadsby, K. Hamed, R. Akolekar, K. H. Nicolaides   +5 more
wiley   +1 more source