Results 101 to 110 of about 42,572 (273)

High-grade vaginal intraepithelial neoplasia and risk of progression to vaginal cancer. a multicentre study of the Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV) [PDF]

open access: yes, 2016
OBJECTIVE: The aim of this study was to analyse the women with high grade vaginal intraepithelial neoplasia (HG-VaIN), in order to identify a subset of women at higher risk of progression to invasive vaginal cancer.
Agarossi, A   +16 more
core  

Diagnostic approach to chronic diarrhoea in adult horses

open access: yesEquine Veterinary Education, Volume 37, Issue 6, Page 328-336, June 2025.
Summary Chronic diarrhoea presents a diagnostic challenge for both human physicians and equine veterinarians. There is currently no consensus in the equine veterinary literature on the definition of chronic diarrhoea. The differential list is extensive and identifying diarrhoea by pathophysiologic mechanism can help remove less likely diagnoses ...
E. Sjolin, A. Lack, L. G. Arroyo
wiley   +1 more source

Trends in cancer mortality in the Americas, 1970-2000 [PDF]

open access: yes, 2017
Background: Data and statistics on cancer mortality over the last decades are available for most developed countries, while they are more difficult to obtain, in a standardized and comparable format, for countries of Latin America.
Bosetti, C.   +5 more
core  

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

open access: yesThe FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang   +7 more
wiley   +1 more source

Prostitution, Condom Use, and Invasive Squamous Cell Cervical Cancer in Thailand [PDF]

open access: yes, 2017
Cervical cancer is probably caused by a sexually transmitted agent. A case-control study was conducted in three hospitals in Thailand to investigate further the role of male sexual behavior, particularly regarding sexual contacts with prostitutes, in the
Christopherson, William M.   +11 more
core  

The G protein‐coupled receptor GPR89A is a novel potential therapeutic target to overcome cisplatin resistance in NSCLC Calu1 cells

open access: yesThe FEBS Journal, EarlyView.
A genome‐wide CRISPR‐Cas9‐based genetic screen in cisplatin‐resistant NSCLC cells revealed 63 potential candidate genes for overcoming cisplatin resistance, including GPR89A. GPR89A, localised in the Golgi, modulates voltage‐gated anion channel activity and is involved in intracellular pH reduction.
Hale Guler Kara   +9 more
wiley   +1 more source

[Analysis of a municipal program of uterine cervical neoplasm prevention]. [PDF]

open access: gold, 2010
Maurícia Brochado Oliveira Soares   +1 more
openalex   +1 more source

Thyroid lesions of neuroendocrine origin? Thinking of a “polka‐dotted” zebra! Case series from three Italian referral centers and review of the literature

open access: yesJournal of Neuroendocrinology, EarlyView.
Thyroid metastases from neuroendocrine neoplasm (NEN) should be considered in case of suspicious thyroid nodules in patients with a positive medical history of NEN, mainly of thoracic origin, even after many years from the initial diagnosis. The differential diagnosis from primary intrathyroidal NEN is challenging.
Tiziana Feola   +62 more
wiley   +1 more source

Trends in cancer mortality in the European Union and accession countries, 1980-2000 [PDF]

open access: yes, 2017
Cancer mortality rates and trends over the period 1980-2000 for accession countries to the European Union (EU) in May 2004, which include a total of 75 million inhabitants, were abstracted from the World Health Organization (WHO) database, together with,
Boyle, P.   +5 more
core  

Biological Consequences and Assessment Methods Analysis of Fixed Orthodontic Appliances on Oral Epithelial Cells: A Systematic Review

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Introduction Fixed orthodontic appliances (OAs) expose the oral mucosa to mechanical traumas and metal ions throughout the whole orthodontic therapy. This review aims to understand the cytological and genetic changes consequent to fixed orthodontic therapy, their clinical implications, and how they can be assessed.
Francesco Paolo Modugno   +6 more
wiley   +1 more source

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