Results 111 to 120 of about 540,986 (276)

Tissue Factor‐High Ovarian Clear Cell Carcinoma Shows Immune‐Cold Features and Preclinical Activity of Tisotumab Vedotin

Cancer Science, EarlyView.
F3/TF‐high ovarian clear cell carcinoma exhibits an immune‐cold phenotype characterized by reduced immune‐cell fractions and attenuated cancer‐cell interferon programs, with frequent B7‐H4 co‐expression. Patient‐derived models show preclinical sensitivity to the TF‐directed antibody–drug conjugate tisotumab vedotin.
Yutaro Mori, Ryo Tamura, Kotaro Takahashi, Kaoru Yamawaki, Tatsuya Ishiguro, Teiichi Motoyama, Koji Okamoto, Kosuke Yoshihara   +7 more
wiley   +1 more source

Ovarian pain in the mare: Clinical implications of mittelschmerz and oestrus‐related behavioural abnormalities

Equine Veterinary Education, EarlyView.
Summary Mittelschmerz is a well‐recognised benign peri‐ovulatory pain syndrome in women and, by physiological analogy, may also occur in mares. In equine practice, peri‐ovulatory ovarian pain has been associated with transient discomfort, colic‐like signs and behavioural changes, although its true clinical relevance remains poorly defined.
G. Marino, V. Biondi, A. Sfacteria, G. Catone, C. Vullo   +4 more
wiley   +1 more source

Comprehensive Histopathological Profiling of Female Genital Tract Neoplasms: Insights from a Two-Year Prospective Study

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: Neoplasms of the female genital tract show considerable histopathological diversity, with leiomyomas being the most frequent benign tumors and carcinomas of the endometrium, cervix, and ovary representing significant malignant entities ...
Shirish S. Chandanwale, Abhishek Tambile, Madhuri Singh Akshi Raj, Nandita Wadhwa, Ranjana Roy   +4 more
doaj   +1 more source

An Outlook on Uterine Neoplasms: From Hormonal and DNA Damaging to Cervical and Endometrial Cancer Development and Minimally Invasive Management. [PDF]

, 2009
Uterine neoplasms are common tumors, formed by endometrial and cervical cancers; endometrial cancer is the fourth most frequently diagnosed cancer in developed countries and the eighth leading cause of cancer death in women, and cervical cancer is the ...
Zizza A., Lorusso V., Leo G., GUIDO, Marcello, VERGARA, DANIELE, VERGARI, UGHETTA, Martignago R., Malvasi A., Tinelli A., Pisanò M.   +9 more
core  

Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion

Histopathology, EarlyView.
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang, Karen L. Talia, W. Glenn McCluggage, Robert A. Soslow, Bin Yang   +4 more
wiley   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

HMGA2 is a highly sensitive marker for DICER1‐related tumours

Histopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner, Anne‐Laure Chong, Naciba Benlimane, Lili Fu, Marc R. Fabian, William D. Foulkes   +5 more
wiley   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Caracterización de mujeres de Las Tunas con lesiones cérvico uterinas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Fundamento: el cáncer cérvico uterino provoca anualmente la muerte de muchas mujeres a nivel mundial, la mayoría en los países en desarrollo.Objetivo: caracterizar a las pacientes estudiadas por lesiones cérvico uterinas, atendidas en el Hospital General
Rabiel Cárdenas Peña, Dianni Pérez Escalona, Ramón Jesús Cruz Pérez, Karen Luz Torres Rojas, Julio Antonio Pérez Pantoja   +4 more
doaj  

Simultaneous use of ovarian transposition with various assisted reproductive technology methods aimed at preserving reproductive function in cancer patients

Клинический разбор в общей медицине
A total of 624,835 cases of malignant neoplasms were registered in 2023 in the Russian Federation (283,179 and 341,656 cases in male and female patients, respectively).
Marina V. Kiseleva, Maksim S. Denisov, Andrey D. Kaprin, Sergey A. Ivanov, Tatyana I. Alba, Lyudmila S. Solovieva, Polina K. Buryan, Anastasiya S. Yakusheva   +7 more
doaj   +1 more source