Results 101 to 110 of about 107,669 (263)

Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]

, 1992
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Mann, Klaus, Spöttl, Gerald, Jüngst, Dieter, Hörmann, Rudolf, Gerbes, Alexander L.   +4 more
core  

Pelvic relapses of uterine neoplasms: transvaginal sonographic and Doppler features

, 2004
Objective. To describe the sonographic and power Doppler features of pelvic relapses in endometrial and cervical cancer. Methods. We retrospectively analyzed the preoperative transvaginal sonographic reports of 45 women with a histological diagnosis of ...
Savelli, Luca, Ferrandina, Gabriella, Scambia, Giovanni, De Iaco, Pierandrea, Rosati, Federica, Testa, Antonia Carla, Basso, Danila, GHI, Tullio   +7 more
core   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

Cancer Science, EarlyView.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

An Unusual Uterine Tumor With Signet Ring Cell Features.

, 2012
In 2004, a 56-year-old woman was diagnosed with Stage IA follicular lymphoma in a cervical lymph node biopsy. The patient experienced total remission after local radiation therapy.
Sarro, R., Bisig, B., Fiche, M., Achtari, C., Ketterer, N., Benhattar, J., de Leval, L.   +6 more
core   +1 more source

Ovulation-stimulation drugs and cancer risks: a long-term follow-up of a British cohort. [PDF]

, 2009
To assess long-term health effects of ovarian-stimulation drugs we followed-up for over 20 years a British cohort of 7355 women with ovulatory disorders, 43% of whom were prescribed ovarian-stimulation drugs, and identified a total of 274 deaths and 367 ...
Overton, C, V A McCormack, Dos Santos Silva, I, McCormack, VA, Wark, PA, Little, V., Overton, C., Hardiman, P, McCormack, V. A., P A Wark, Nieto, J., Davies, M, Davies, M., I dos Santos Silva, Little, V, A B MacLean, P Hardiman, MacLean, A. B., Nieto, J, M Davies, Dos Santos Silva, I., Mayer, D, J Nieto, Silva, I dos Santos, Wark, P. A.; id_orcid, Hardiman, P., C Overton, V Little, Maclean, AB, D Mayer, Mayer, D.   +30 more
core   +1 more source

Rectal wall dose-volume effect of pre- or post KUSHEN Ningjiaos relationship with 3D brachytherapy in cervical cancer patients

Radiation Oncology, 2019
Background The present prospective study evaluated the safety and efficacy of the rectum following KUSHEN Ningjiaos in cervical cancer. We compared rectal wall changes during brachytherapy with or without KUSHEN Ningjiaos in cervical cancer patients and ...
Xiaojuan Li, Cheng Xiao, Yilin Kong, Weiwei Guo, Wenting Zhan, Gong Li, Xuetao Wang, Bailin Zhang, Lei Gao   +8 more
doaj   +1 more source

Cervical Small Cell Neuroendocrine Carcinoma Initially Detected on Cytology: Diagnostic Pitfalls and Clues

Cytopathology, EarlyView.
This case describes the initial detection of cervical small cell neuroendocrine carcinoma on conventional endometrial and cervicovaginal liquid‐based cytology. Given its rarity and high aggressiveness, early recognition and rapid, intensive treatment are crucial for improving patient outcomes.
Yesul Jeong
wiley   +1 more source

Comprehensive Histopathological Profiling of Female Genital Tract Neoplasms: Insights from a Two-Year Prospective Study

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: Neoplasms of the female genital tract show considerable histopathological diversity, with leiomyomas being the most frequent benign tumors and carcinomas of the endometrium, cervix, and ovary representing significant malignant entities ...
Shirish S. Chandanwale, Abhishek Tambile, Madhuri Singh Akshi Raj, Nandita Wadhwa, Ranjana Roy   +4 more
doaj   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source