Results 141 to 150 of about 138,873 (259)

Elevating and empowering reproductive futures: Pediatric and adolescent gynecology's specialized care across the globe

International Journal of Gynecology &Obstetrics, Volume 171, Issue 2, Page 528-537, November 2025.
Abstract Pediatric and adolescent gynecology (PAG) is an expanding subspecialty of obstetrics and gynecology that addresses the reproductive health needs of girls and young women worldwide. In regions with limited subspecialist healthcare providers, general obstetricians, gynecologists, and nurse‐midwives, frontline healthcare providers provide ...
Nichole A. Tyson, Méabh Ní Bhuinneáin, Hema Divakar, Lauren Mauger, Judith Simms Cendan, Marisa Labovsky, FIGO Committee on Adolescent and Youth Health   +6 more
wiley   +1 more source

Cancer Prevention and Therapy With Nutritional Science: Addressing the Gap in Medical Education and Practice

MedComm, Volume 6, Issue 11, November 2025.
A plant‐based diet reduces the risk of cancer by providing essential nutrients and phytochemicals that contain anticancer properties. Osteopathic medicine's holistic approach emphasizes the interconnectedness of body systems and lifestyle factors, including nutrition, to promote overall health and prevent disease.
Taylor E. Collignon, Anupam Bishayee
wiley   +1 more source

The association between oral risk assessment and obstetric and newborn outcomes

Pregnancy, Volume 1, Issue 6, November 2025.
Abstract Background Periodontal disease in pregnancy is a known risk factor for adverse obstetric and offspring outcomes, including preeclampsia and preterm birth. The American College of Obstetricians and Gynecologists (ACOG) recommends screening all pregnant patients on their first obstetric visit with a simple, self‐administered, three‐question oral
Carolina Martinez‐King, Charlie Rose, Krystle M. Perez, Olivia Brandon, Annika Sahota, Kanika Nallaseth, Tommy Yang, Sophia Tibayan, Shruti Kulkarni, Abdul Hameed, Kathryn J. Gray, Thomas R. Wood, Gregory C. Valentine   +12 more
wiley   +1 more source

Research Progress of RAD51AP1 in Malignant Tumors of the Female Reproductive System

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
RAD51AP1 is highly expressed in malignant tumors of the female reproductive system, exerting a pro‐carcinogenic effect and showing a close association with poor prognosis. High expression of RAD51AP1 can promote tumor cell proliferation, invasion, migration, and stemness maintenance, inhibit apoptosis, and mediate chemoresistance as well as ...
Chengguo Zhang, Xiaoyang Liu, Zizhang Li, Jiayao Han, Jun Liang, Nan Zhou   +5 more
wiley   +1 more source

Pelvic lymph node dissection in the treatment of cervical and uterine neoplasms – correlation with the histologic type and disease stage

Oncolog-Hematolog.ro, 2021
Eugen Bratucu, Laurenţiu Simion, Alexandru C. Grigorescu, M Marincaş, Livia Iordache, Virgiliu Mihail Prunoiu, Maria Manuela Răvaş   +6 more
openaire   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, Volume 19, Issue 10, Page 2833-2859, October 2025.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, Volume 12, Issue 39, October 20, 2025.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

Lithium Exposure Causes Trophoblast Cuproptosis by Upregulating FOXO1/STEAP4 Axis in Unexplained Miscarriage

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Li exposure up‐regulates FOXO1 expression levels and thus promotes FOXO1‐mediated STEAP4 transcription, up‐regulating STEAP4 levels. Subsequently, STEAP4 up‐regulates intracellular Cu+ ion levels and causes cuproptosis, which further induces miscarriage.
Shuaishuai Xing, Yanbing Lin, Yi Sun, Xiaoping Yue, Qigang Fan, Jisheng Nie, Zhihong Zhang, Yajing Liu, Juntang Yang, Qingzheng Kang, Yanxin Wang, Haijun Yan, Chan Tian, Ying Chang, Huidong Zhang   +14 more
wiley   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source