Effects of the selective progesterone receptor modulator asoprisnil on uterine artery blood flow, ovarian activity, and clinical symptoms in patients with uterine leiomyomata scheduled for hysterectomy [PDF]
Introduction: Asoprisnil, a novel orally active selective progesterone receptor modulator, is being studied for the management of symptomatic uterine leiomyomata. The exact mechanism of action is not yet discerned.
Williams, A.R.W. +21 more
core +1 more source
Phloroglucinol is commonly used to alleviate dysmenorrhoea and stomach cramps. However, there is little evidence of phloroglucinol in the mechanism of primary dysmenorrhoea (PD) development. In this study, a PD rat model was established.
Wenhui Yang +8 more
doaj +1 more source
Background: In obesity, the adipose tissue becomes a very significant endocrine organ producing different factors called adipokines, such as leptin, adiponectin and kisspeptin; however, no data are available about their actions on uterine contraction in ...
Róbert Gáspár +16 more
doaj +1 more source
Cost-effectiveness of magnetic resonance-guided focused ultrasound surgery for treatment of uterine fibroids [PDF]
OBJECTIVE: To estimate the cost-effectiveness of a treatment strategy for symptomatic uterine fibroids, which starts with Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) as compared with current practice comprising uterine artery ...
Cairns, JA +6 more
core +1 more source
Endothelin-dependent vasoconstriction in human uterine artery: application to preeclampsia. [PDF]
BACKGROUND: Reduced uteroplacental perfusion, the initiating event in preeclampsia, is associated with enhanced endothelin-1 (ET-1) production which feeds the vasoconstriction of uterine artery. Whether the treatments of preeclampsia were effective on ET-
Clotilde Dechanet +5 more
doaj +1 more source
Characterization of the tissue-level Ca2+signals in spontaneously contracting human myometrium [PDF]
In the labouring uterus, millions of myocytes forming the complex geometrical structure of myometrium contract in synchrony to increase intrauterine pressure, dilate the cervix and eventually expel the foetus through the birth canal.
Blanks, Andrew M. +9 more
core +1 more source
Randomised comparison of uterine artery embolisation (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results [PDF]
Objective: To compare the long-term results of uterine artery embolisation (UAE) with surgery for women with symptomatic uterine fibroids. Design Pragmatic, open, multicentre, randomised trial. Setting Twenty-seven participating UK secondary care centres.
MA Lumsden +15 more
core +1 more source
Different volatile agents with different physicochemical properties affect uterine contraction, amount of bleeding, and APGAR score in different ways. The objective of this study was to evaluate the effects of different volatile agents, i.e., sevoflurane
RR. Pramada Resvita +2 more
doaj +1 more source
Blood vessel assessment using computed tomography : Effects of ephedrine on uterine artery
Background: Ephedrine increased blood pressure due to the contractile properties of resistance vessels. Excessive contraction of the uterine arteries might cause fetal distress. This study was to determine the diameter of the uterine artery of female New
Yibo Yin +6 more
doaj +1 more source
The role of mitochondria in uterine contractions [PDF]
The contractile activity of smooth muscle, like that of all muscle types, is controlled by changes in the myoplasmic free calcium ion concentration [ 131. Muscle concentration is initiated by a rise in the calcium concentration and relaxation occurs when the calcium level has been lowered to the initial level. It is known that extra-cellular calcium is
Wikström, Mårten +2 more
openaire +2 more sources

