Results 31 to 40 of about 410,360 (291)

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

Advanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao, Jian Zhang, Qi Qian, Min Jiang, Yu Liu, Yan Geng, Nan Cui, Qi Guo, Jie Guo   +8 more
wiley   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Residual-Noise-Aware Uterine Contraction Detection From Electrohysterography Using Bayesian Tensor Decomposition

IEEE Access
Muscle cell electrical activity serves as the fundamental trigger for mechanical force generation, underpinning its widespread applicability in clinical practice.
Caiying Wu, Luyi Ruan, Yertayeva Zhainagul, Jinshan Xu   +3 more
doaj   +1 more source

Predicting preterm labour by means of uterine artery doppler velocimetry during peak uterine contraction in patients with normal cervical length

Advances in Human Biology, 2019
Background: This study was conducted to evaluate the uterine artery Doppler velocimetry (UADV) during peak uterine contraction in order to predict preterm labour in Iranian women with a normal cervical length. Materials and Methods: This cohort study was
Mahsa Naemi, Laleh Eslamian, Nastaran Teimoory, Maryam Moshfeghi, Ali Tajik   +4 more
doaj   +1 more source

Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking

Diagnostics, 2020
Magnetic resonance imaging (MRI) is a promising non-invasive imaging technique that can be safely used to study placental development and function. However, studies of the human placenta performed by MRI are limited by uterine motion and motion in the ...
Thomas Martin, Carla Janzen, Xinzhou Li, Irish Del Rosario, Teresa Chanlaw, Sarah Choi, Tess Armstrong, Rinat Masamed, Holden H. Wu, Sherin U. Devaskar, Kyunghyun Sung   +10 more
doaj   +1 more source

A Broad-Spectrum Chemokine Inhibitor Blocks Inflammation-Induced Myometrial Myocyte–Macrophage Crosstalk and Myometrial Contraction

Cells, 2021
Prophylactic administration of the broad-spectrum chemokine inhibitor (BSCI) FX125L has been shown to suppress uterine contraction, prevent preterm birth (PTB) induced by Group B Streptococcus in nonhuman primates, and inhibit uterine cytokine/chemokine ...
Adam Boros-Rausch, Oksana Shynlova, Stephen James Lye   +2 more
doaj   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Prenatal Detection of Arthrogryposis Multiplex Congenita, Present State and Future Perspectives

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is a heterogeneous group of conditions characterized by congenital contractures in at least two different body regions. Despite increasingly widespread prenatal ultrasound screening, prenatal detection rates for AMC remain disappointingly low, with fewer than half of affected fetuses diagnosed before ...
Arda Arduç, Jill K. Tjon, Ingeborg H. Linskens, Nienke Kok, Julia Slootbeek, Maria B. Tan‐Sindhunata, Harold van Bosse, Sara Lemin, Isabel Filges, Klaus Dieterich, Remco Jansen, Ani Samargian, Victoria Castillo‐Sánches, Judith G. Hall, Johanna I. P. de Vries   +14 more
wiley   +1 more source

Over the edge: Empirical evidence for the cliff‐edge model of obstetric selection

The Anatomical Record, EarlyView.
Abstract The cliff‐edge model of obstetric selection maintains that larger neonates and smaller birth canals confer a positive selective advantage until labor becomes obstructed and vaginal delivery is no longer possible, eliciting an abrupt reduction in fitness.
Laura M. Watson, Pierre Frémondière, Kaspar Staub, Philipp Mitteroecker, Barbara Fischer, Martin Haeusler, Nicole M. Webb   +6 more
wiley   +1 more source

3D power Doppler ultrasound assessment of placental perfusion during uterine contraction in labor [PDF]

, 2017
香川大学Kagawa University博士（医学）Introduction To assess placental perfusion during spontaneous or induced uterine contraction in labor at term using placental vascular sonobiopsy (PVS) by 3D power Doppler ultrasound with the VOCAL imaging analysis program ...
Sato, Miki, サトウ, ミキ, 佐藤, 美樹   +2 more
core   +1 more source