Results 41 to 50 of about 30,525 (282)

A Broad-Spectrum Chemokine Inhibitor Blocks Inflammation-Induced Myometrial Myocyte–Macrophage Crosstalk and Myometrial Contraction

open access: yesCells, 2021
Prophylactic administration of the broad-spectrum chemokine inhibitor (BSCI) FX125L has been shown to suppress uterine contraction, prevent preterm birth (PTB) induced by Group B Streptococcus in nonhuman primates, and inhibit uterine cytokine/chemokine ...
Adam Boros-Rausch   +2 more
doaj   +1 more source

ERK MAP kinases regulate smooth muscle contraction in ovine uterine artery: effect of pregnancy [PDF]

open access: yes, 2002
The present study investigated the potential role of extracellular signal-regulated kinase (ERK) in uterine artery contraction and tested the hypothesis that pregnancy upregulated ERK-mediated function in the uterine artery. Isometric tension in response
Daliao Xiao, Lubo Zhang
core   +1 more source

Salvia sclarea L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting the Ca2+–MLCK–MLC20 Signaling Cascade: An Ex Vivo and In Vivo Study

open access: yesAntioxidants, 2020
Salvia sclarea essential oil is used as an aromatic therapy for dysmenorrhea. Sclareol—one of the natural products isolated from S. sclarea—displays anti-inflammatory and antioxidant activities; however, researchers have not yet evaluated the mechanism ...
Jennifer Wong   +9 more
doaj   +1 more source

Uterine contraction and physiological mechanisms of modulation [PDF]

open access: yes, 1993
Control of the smooth muscle in the uterus (the myometrium), is of vital importance during pregnancy and parturition. It is therefore understandable that several physiological mechanisms (neuronal, hormonal, metabolic, and mechanical) play a role in the ...
S. Wray
core   +1 more source

Phloroglucinol inhibits oxytocin-induced contraction in rat gastric circular muscle and uterine smooth muscle [PDF]

open access: yes, 2022
Phloroglucinol is commonly used to alleviate dysmenorrhoea and stomach cramps. However, there is little evidence of phloroglucinol in the mechanism of primary dysmenorrhoea (PD) development. In this study, a PD rat model was established.
Wenhui Yang (82599)   +8 more
core   +1 more source

The Effect of Vitamin D3 Supplementation on Increases of Levator Ani Contraction Strength in Women with Uterine Prolapse

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2020
Objective: To investigate the differences of levator muscle contraction strength after vitamin D3 supplementation, thus it is expected that the administration of vitamin D3 can reduce the incidence of uterine prolapse recurrence after reconstructive ...
Nenny Yoanitha   +3 more
doaj   +1 more source

Single-cell mechanics and calcium signalling in organotypic slices of human myometrium [PDF]

open access: yes, 2015
The information that connects genotypes and phenotypes is essentially embedded in research articles written in natural language. To facilitate access to this knowledge, we constructed a framework for the curation of the scientific literature studying the
Loftus, Fiona C.   +3 more
core   +1 more source

Muscarinic receptor blockade with oxybutynin reduces spontaneous and induced uterine muscle contractions

open access: yesPregnancy
Objective The uterus and the bladder have striking physiologic and anatomic similarities. Anticholinergic medications are commonly used to treat “overactive bladder” by targeting M2 and M3 muscarinic receptors.
Anthony G. Visco   +5 more
doaj   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

Implantation‐On‐Chip: An AI‐Based Platform for Monitoring the Embryo Trophoblast–Endometrial Stroma Cross Talk With Xenobiotics Interference

open access: yesAdvanced Intelligent Systems, EarlyView.
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi   +12 more
wiley   +1 more source

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