Results 91 to 100 of about 172,392 (291)

Possibilities for therapy of a comorbidity of uterine myoma and benign breast dysplasias

Репродуктивная эндокринология, 2017
Objective. To improve the reproductive health of women with benign breast dysplasia (BBD) and uterine myoma, by elaborating a differentiated approach to preventing and treating comorbid diseases. Subject and methods. The investigation included 175 women
В. Е. Радзинский, И. М. Ордиянц, М. Н. Масленникова, Е. А. Павлова, В. В. Карданова   +4 more
doaj   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Harnessing Vaginal Probiotics for Enhanced Management of Uterine Disease and Reproductive Performance in Dairy Cows: A Conceptual Review

Animals
Uterine disease in cattle impairs reproductive performance and profitability and increases antibiotic use and antimicrobial resistance. Thus, probiotics offer a promising alternative therapy.
Mounir Adnane, Ronan Whiston, Taurai Tasara, Ulrich Bleul, Aspinas Chapwanya   +4 more
doaj   +1 more source

The global burden of polycystic ovary syndrome, endometriosis, uterine fibroids, cervical cancer, uterine cancer, and ovarian cancer from 1990 to 2021

BMC Public Health
Background Globally, common gynecological disorders such as Polycystic Ovary Syndrome (PCOS), endometriosis, uterine fibroids (non-malignant gynecological diseases), as well as cervical cancer, uterine cancer, and ovarian cancer (gynecological cancers ...
Wei-Zhen Tang, Qin-Yu Cai, Kang-Jin Huang, Wei-Ze Xu, Jia-Zheng Li, Yun-Ren Pan, Hong-Yu Xu, Yi-Fan Zhao, Ting-He Sheng, Zhi-Mou Li, Tai-Hang Liu, Ying-Bo Li   +11 more
doaj   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Uterine diseases in bovine 1. Epidemiological and etiologic aspects

, 1996
peer reviewedAssessing the frequency of metritis shows the animal uterine health as well as the herd . The practitioner prefers to use vaginal examination.
Houtain, J. Y., Laurent, Y., Hanzen, Christian   +2 more
core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Effects of postpartum acetylsalicylic acid on uterine diseases and reproductive performance in dairy cattle. [PDF]

JDS Commun, 2021
Barragan AA, Bas S, Hovingh E, Byler L.
europepmc   +1 more source

Linzagolix – new perspectives in the pharmacotherapeutic management of uterine fibroids and endometriosis

Uterine fibroids and endometriosis are among the most common conditions encountered in gynaecological practice. Fibroids affect 30–70% of women, with up to half experiencing symptoms that significantly impair quality of life (QoL), including anaemia ...
Tomasz Paszkowski
core   +1 more source