Results 71 to 80 of about 172,392 (291)

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim   +11 more
wiley   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura   +2 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh   +1 more
wiley   +1 more source

Uterine sarcoma – current perspectives

open access: yes, 2017
Charlotte Benson,1 Aisha B Miah1,2 1Sarcoma Unit, Royal Marsden Hospital, 2Department of Radiotherapy and Imaging, The Institute of Cancer Research, London, UK Abstract: Uterine sarcomas comprise a group of rare tumors with differing tumor biology ...
Benson C, Miah AB
core  

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang   +7 more
wiley   +1 more source

CLINICAL AND MORPHOLOGICAL CHARACTERISTICS AND PROGNOSTIC SIGNIFICANCE OF THE CONTENTS OF PD-ECGF, TGF-β, KI67 IN ENDOMETRIUM AT LARGE UTERINE LEIOMYOMA

open access: yesКлиническая практика, 2016
The endometrium may be the most convenient object of forecasting the development of the large uterine fibroid, as the object is available in the diagnosis of diseases of the uterus, changes in its cytokine profile linked with the growth of uterine ...
S I Askolskaya   +4 more
doaj   +1 more source

Development of immunocompetent models for primary and metastatic ER+ breast cancer

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull   +5 more
wiley   +1 more source

Using cluster of differentiation CD 38, CD 45 and CD 95 as a method of primary diagnosis of uterine fibroids

open access: yesJournal of Education, Health and Sport, 2017
Uterine myoma is one of the first places among gynecological diseases. There is a rise of the number of pathology diagnoses among young women. Currently inUkrainethere is no single approved laboratory method for screening of uterine myomas.
I. V. Savytskyi   +5 more
doaj   +3 more sources

Risk Factors for Uterine Disease in Dairy Cows

open access: yesEDIS, 2012
Uterine diseases are highly prevalent in high-producing dairy cows. Predictors of uterine disease include traditional risk factors, BHBA blood concentration, NEFA blood concentration, neutrophil glycogen stores, and calcium.
Klibs N.A. Galvão
doaj   +1 more source

New Insights Into Postpartum Uterine Diseases Of Dairy Cows

open access: yes, 2015
Uterine diseases of dairy cows have a negative impact in the dairy industry because they are prevalent, contribute to economic losses and are an animal welfare issue.
Machado, Vinicius
core  

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