Results 61 to 70 of about 2,393,029 (295)

Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss [PDF]

open access: yes, 2012
Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood.
Nicou, M   +88 more
core   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

open access: yesAdvanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa   +5 more
wiley   +1 more source

Robotic Surgery Conservative Approaches for Uterine Adenomyosis: A Systematic Review

open access: yesSurgeries
Background/Objectives: Adenomyosis is a common disorder of the uterus in those of reproductive age. Robotic-assisted surgery has been adopted to address the technical challenges of adenomyomectomy.
Mario Ardovino   +8 more
doaj   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

open access: yesAdvanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen   +7 more
wiley   +1 more source

Association of calving factors and labor duration with postpartum uterine health in Holstein cattle

open access: yesJournal of Dairy Science
: The objective of this observational study was to investigate the association between the duration of labor, calving assistance, and uterine diseases, as well as estimate a reference time to be used as a guideline for providing calving assistance based ...
J.W. Bauer   +3 more
doaj   +1 more source

A large submucous uterine leiomyoma and pregnancy: clinical case [PDF]

open access: yesĶazaķstannyṇ Klinikalyķ Medicinasy, 2019
Leiomyoma (or uterine myoma) is the most widespread tumor, which occupies the 2nd place in the structure of gynecological diseases, after inflammatory diseases of the pelvic organs.
Tatyana Sergeevna Slobodchikova   +1 more
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

open access: yesAdvanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh   +22 more
wiley   +1 more source

Towards understanding the myometrial physiome: approaches for the construction of a virtual physiological uterus [PDF]

open access: yes, 2007
Premature labour (PTL) is the single most significant factor contributing to neonatal morbidity in Europe with enormous attendant healthcare and social costs. Consequently, it remains a major challenge to alleviate the cause and impact of this condition.
Bin Wang   +19 more
core   +1 more source

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