Results 61 to 70 of about 30,651 (251)
A potential diagnostic biomarker: Proteasome LMP2/b1i-differential expression in human uterus neoplasm [PDF]
, 2012 Uterine leiomyosarcoma (ULMS) develops more often in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of uterine ULMS
Akiko Horiuchi +5 more
core +1 more source
Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions
Clinical Endocrinology, EarlyView.ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley +1 more source
Sokoto Journal of Medical Laboratory Science, 2016 Uterine leiomyoma is a benign tumour which is non-cancerous from smooth muscle tissue that develops from smooth muscle layer (myometrium) from the uterus.
Mohammed, I.*, Hussein, A.S., Kaoje, A.U., Tangaza, A.M.
doaj
Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas [PDF]
, 2017 Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus.
Aaltonen, Lauri A. +11 more
core +1 more source
Histopathology, EarlyView.GREB1‐rearranged uterine tumours share DNA methylation profiles with UTROSCTs, supporting a close relationship. Despite differences in morphology and genomic complexity, their epigenetic similarity supports the inclusion of these tumours within the UTROSCT spectrum. Background and objectives GREB1‐rearranged uterine tumours encompass a group of uterine
Cheng‐Han Lee +12 more
wiley +1 more source
Epidemiologic peculiarities of combined hyperproliph erative processes of female reproductive system [PDF]
Medičnì Perspektivi, 2013 The study involved 622 women of reproductive age with such hyperproliferative processes of the pelvic organs as uterine leiomyoma, endometrial hyperplasia and endometriosis. We studied main epidemiological factors inherent in these diseases.
Potapov V.O. +4 more
doaj
Current Oncology, 2022 Background/Aim: Patients with uterine sarcoma comprise 2–5% of all patients with uterine malignancies; however, the morbidity of uterine sarcoma is low compared with that of other gynecological cancers.
Saya Tamura +5 more
doaj +1 more source
Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass [PDF]
, 2013 Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs.
Alappan, Narendrakumar +4 more
core +2 more sources
Biomarkers in uterine leiomyoma [PDF]
Fertility and Sterility, 2013 Biomarkers are biologic compounds that are easily accessible and reflect normal physiology or pathology. They are useful in a variety of clinical situations that involve detection of subclinical disease, risk stratification, preoperative planning, and monitoring treatment.
Gary, Levy +4 more
openaire +2 more sources
Molecular pathology of phyllodes tumours of the breast—much more than MED12
Histopathology, EarlyView.Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang +3 more
wiley +1 more source