Results 161 to 170 of about 359,174 (252)

Ovarian pain in the mare: Clinical implications of mittelschmerz and oestrus‐related behavioural abnormalities

Equine Veterinary Education, EarlyView.
Summary Mittelschmerz is a well‐recognised benign peri‐ovulatory pain syndrome in women and, by physiological analogy, may also occur in mares. In equine practice, peri‐ovulatory ovarian pain has been associated with transient discomfort, colic‐like signs and behavioural changes, although its true clinical relevance remains poorly defined.
G. Marino, V. Biondi, A. Sfacteria, G. Catone, C. Vullo   +4 more
wiley   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Incidence of Gynecological Cancers Is Rising in Northern Iran: A Population-Based, Serial Cross-Sectional Joinpoint Regression Study. [PDF]

Health Sci Rep
Amouzadeh-Lichahi M, Karimzadhagh S, Zaresharifi N, Jafari A, Karimian P, Jafari M, Sadeghi G, Yazdanipour MA.   +7 more
europepmc   +1 more source

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

The FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro, Aurore Dougé, Klara Krpina, Lea‐Marie Schmitz, Christopher Forcados, Fatemeh Kaveh, Andrea Estrella Arias‐Díaz, Pascal Gelebart, Emmet McCormack, Renata Stripecke, Miguel Abal, Ben Davidson, Else Marit Inderberg, Sébastien Wälchli   +13 more
wiley   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

From Leiomyoma to Smooth Muscle Tumor of Uncertain Malignant Potential: A Rare Recurrent Right Retroperitoneal Mass in a Young Male. [PDF]

Cureus
Preetham Y, Thyavihally Y, Gundavda M, Kulkarni B, Shah A.   +4 more
europepmc   +1 more source

HMGA2 is a highly sensitive marker for DICER1‐related tumours

Histopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner, Anne‐Laure Chong, Naciba Benlimane, Lili Fu, Marc R. Fabian, William D. Foulkes   +5 more
wiley   +1 more source

Massive uterine angiomyolipoma mimicking uterine leiomyoma in a 49-year-old woman. [PDF]

Qatar Med J
Manikyam S, Kalaimani T, Srianand A, Muniraj F.   +3 more
europepmc   +1 more source

Distinct Rb expression pattern in HPV‐associated neuroendocrine carcinomas of the uterine cervix

Histopathology, EarlyView.
Most uterine cervical neuroendocrine carcinoma (UCNEC) cases are HPV‐associated and are characterized by partial loss of Rb, p16 overexpression, and cyclin D1 negativity. A minority of UCNECs exhibit a distinct pattern, characterized by HPV negativity, retained Rb expression, focal p16 expression and cyclin D1 positivity.
Nobuko Yasutake, Misato Komamizu, Takeshi Iwasaki, Ryosuke Kuga, Tomomi Manako, Mikiko Hashisako, Rina Jiromaru, Tomoko Sho, Norihito Yuge, Kenzo Sonoda, Hideaki Yahata, Yoshinao Oda, Hidetaka Yamamoto   +12 more
wiley   +1 more source

Diffuse large B-cell lymphoma involving the vagina and a pre-existing uterine leiomyoma. [PDF]

Radiol Case Rep
Yagi F, Yamagami W, Ueno A, Kiyokawa S, Nogami Y, Sakurai M, Masuda K, Jinzaki M.   +7 more
europepmc   +1 more source