Results 171 to 180 of about 152,642 (298)

Cervical cancer [PDF]

open access: yes
Revised December 2016There are five main types of cancer that affect a woman\ue2\u20ac\u2122s reproductive organs: cervical, ovarian, uterine, vaginal, and vulvar. As a group, theyare referred to as gynecologic (GY-neh-kuh-LAH-jik) cancer.

core  

Cadaveric addendum to the consensus on ultrasound‐based lymph‐node staging in gynecological cancer

open access: yes
Ultrasound in Obstetrics &Gynecology, EarlyView.
D. Fischerova   +13 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

TONSL Promotes Hepatocellular Carcinoma Progression by Inhibiting Apoptosis Through Homologous Recombination Repair

open access: yesCancer Science, EarlyView.
In hepatocellular carcinoma, the 8q24.3 locus is frequently amplified and is associated with tumor‐specific overexpression of TONSL. TONSL promotes homologous recombination repair through RAD51, limits γH2AX accumulation and apoptosis, supports tumor growth, and its loss increases sensitivity to poly (ADP‐ribose) polymerase (PARP) inhibition.
Akinori Tsujimoto   +16 more
wiley   +1 more source

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy

open access: yesCancer Science, EarlyView.
MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley   +1 more source

Endometrial Dysfunction in Women with Ovarian and Uterine Tumors: What Is Known and What Should Be Learned? [PDF]

open access: yesInt J Mol Sci
Mikhaleva LM   +7 more
europepmc   +1 more source

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