Improvement of Microangiopathy in A Systemic Sclerosis Patient Following Hysterectomy for Leiomyoma: A Potential Role of Neoplasia. [PDF]
Nigro A+5 more
europepmc +1 more source
Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang+7 more
wiley +1 more source
A genome‐wide CRISPR‐Cas9‐based genetic screen in cisplatin‐resistant NSCLC cells revealed 63 potential candidate genes for overcoming cisplatin resistance, including GPR89A. GPR89A, localised in the Golgi, modulates voltage‐gated anion channel activity and is involved in intracellular pH reduction.
Hale Guler Kara+9 more
wiley +1 more source
Complete Cystic Degeneration of a Uterine Myoma Posing a Diagnostic Dilemma. [PDF]
Dibaba AD+8 more
europepmc +1 more source
ABSTRACT Renal cell carcinoma is a heterogeneous disease with diverse phenotypes. Renal cell carcinoma classification is based on morphological and molecular characteristics and falls into 2 main categories: clear cell renal cell carcinoma and non‐clear cell renal cell carcinoma.
Shotaro Nakanishi, Junichi Inokuchi
wiley +1 more source
Quantitative Classification of Uterine Myoma Perfusion on DCE-MRI: Retrospective Analysis of Data and Clinical Implications. [PDF]
Bruszewski A+3 more
europepmc +1 more source
Re: Nonmelanomatous Skin Cancer Following Cervical, Vaginal, and Vulvar Neoplasms:Etiologic Association [CORRESPONDENCE] [PDF]
Frisch, Morten+4 more
core
Clinical Factors Affecting the Quality of Life of Women With Endometriosis
ABSTRACT Aim The study aimed to analyse selected clinical data affecting the quality of life of women with endometriosis. Design A cross‐sectional study. Method The study was conducted in 2020–2022 among 425 women with endometriosis receiving health care. A diagnostic survey method with a questionnaire technique was used.
Agnieszka Bień+6 more
wiley +1 more source
Inflammatory myofibroblastic tumour of cervix: Uncommon pathology in an unlikely location - A literature review. [PDF]
Bhardwaj B+5 more
europepmc +1 more source
A rare case with synchronous gastric gastrointestinal stromal tumor, pancreatic neuroendocrine tumor, and uterine leiomyoma [PDF]
core +1 more source