Results 61 to 70 of about 152,642 (298)

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

ROLE OF HEREDITARY FACTORS IN THE DEVELOPMENT OF GLIAL BRAIN TUMORS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Background. The analysis data on the malignant neoplasms incidence among first-degree relatives of probands with glial brain tumors are presented. Goal.
Pashkevich A. M., Antonenkova N. N., Malko M. V.   +2 more
doaj   +1 more source

Endobody: Genetically Encodable Nanobody‐CPP Chimeras for Degradation of Membrane and Extracellular Proteins

Advanced Science, EarlyView.
We introduced genetically encodable, receptor‐independent nanobody‐CPP chimeras, termed endobodies, as robust and modular membrane protein degraders. Additionally, proteasome‐targeting domain (PTD)‐tethered endobody demonstrates further enhanced degradation potency.
Chengjian Zhou, Huiping He, Simin Xia, Xi Chen   +3 more
wiley   +1 more source

Radiation-Induced Uterine Carcinosarcoma after Concurrent Chemoradiotherapy for Cervical Squamous Cell Carcinoma [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2018
Objective To describe a case of radiation-induced uterine carcinosarcoma 6 years after a cervical squamous cell carcinoma treatment, which imposed some diagnostic and management challenges.
Joana Moreira-Barros, Kuan-Gen Huang, Tsung-Hsun Tsai   +2 more
doaj   +2 more sources

Implantation‐On‐Chip: An AI‐Based Platform for Monitoring the Embryo Trophoblast–Endometrial Stroma Cross Talk With Xenobiotics Interference

Advanced Intelligent Systems, EarlyView.
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi, Valentina Lacconi, Arianna Mencattini, Micol Massimiani, Dolores Lobresca, Gaia Posanzini, Alessia Riccardi, Paola Casti, Michele D’Orazio, Gianni Antonelli, Giorgia Curci, Luisa Campagnolo, Eugenio Martinelli   +12 more
wiley   +1 more source

A reassessment of uterine neoplasms originally diagnosed as leiomyosarcomas [PDF]

Cancer, 1978
Twenty-eight uterine tumors originally diagnosed as leiomyosarcomas were histologically reclassified without prior knowledge of follow-up or clinical data. Thirteen (46%) neoplasms were reinterpreted as cellular or pleomorphic leiomyomas. They had sparse mitotic activity with three or fewer mitotic figures per 10 high power microscopic fields (MF/10 ...
W R, Hart, J K, Billman
openaire   +2 more sources

The "Other" Uterine Mesenchymal Neoplasms: Recent Developments and Emerging Entities.

Uterine mesenchymal neoplasms are a challenging group of tumors that often show overlapping morphologic features and immunohistochemical profiles.
Pinto, Andre, Bennett, Jennifer A
core   +1 more source

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

American Journal of Hematology, EarlyView.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim, Radhika Gangaraju, Omid Jafari, Zihan Yang, Joyce W. T. Tiong, Elizabeth C. L. Chiang, Shengling Ma, Jun Y. Jiang, Justine Ryu, Barbara D. Lam, Mrinal Ranjan, Ang Li   +11 more
wiley   +1 more source

Comprehensive Histopathological Profiling of Female Genital Tract Neoplasms: Insights from a Two-Year Prospective Study

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: Neoplasms of the female genital tract show considerable histopathological diversity, with leiomyomas being the most frequent benign tumors and carcinomas of the endometrium, cervix, and ovary representing significant malignant entities ...
Shirish S. Chandanwale, Abhishek Tambile, Madhuri Singh Akshi Raj, Nandita Wadhwa, Ranjana Roy   +4 more
doaj   +1 more source

Presence of histopathological premalignant lesions and infection caused by high-risk genotypes of human papillomavirus in patients with suspicious cytological and colposcopy results: A prospective study [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. In patients with premalignant cervical lesions, human papillomavirus (HPV) infection, at any moment, may be spontaneously eliminated, or may persist or transform cervical epithelium from a lower to a higher degree.
Golubović Mileta, Lopičić Milena, Terzić Nataša, Đurović Marija, Mugoša Boban, Mijović Gordana   +5 more
doaj   +1 more source