Results 71 to 80 of about 598,872 (375)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Carcinoma microinvasor do colo uterino em paciente de 14 anos: relato de caso e revisão da literatura [PDF]

, 2009
CONTEXT: Cancer of the uterine cervix is rare during adolescence. The reported rates are 0/100,000 adolescents aged 10 to 19 years and 1.7/100,000 women aged 20 to 24 years.
BIANCHI, Mônia Steigleder, COSTA, Juvenal Soares Dias da, DUARTE, Geraldo, GONÇALVES, Carla Vitola, KARAM, Fabine, MARCOLIN, Alessandra Cristina, QUINTANA, Silvana Maria   +6 more
core   +1 more source

Carcinosarcoma of uterus

Radiology Case Reports, 2023
Uterine carcinosarcoma, which is categorized as high-grade endometrial cancer, is an uncommon kind of malignant gynecological neoplasms. Clinically, this tumor frequently affects menopausal women and the main symptom is abnormally postmenopausal vaginal ...
Ho Xuan Tuan, MD, PhD, Nguyen Minh Duc, MD, Cao Minh Tri, MD, Huynh-Thi Do Quyen, MD, Pham Xuan Dung, MD, PhD   +4 more
doaj  

Joint disease mapping of breast, uterine, and ovarian cancers in cities of Isfahan Province from 2005 to 2010 using spatial shared component model

International Journal of Preventive Medicine, 2021
Background: Breast, uterine, and ovarian cancers are the most prevalent types of cancers among women. The aim of this study was to estimate the relative risk of these cancers and recognizing spatial patterns of their shared and specific risk factors in ...
Marzieh Nasr, Behzad Mahaki, Mehdi Kargar, Pejman Aghdak   +3 more
doaj   +1 more source

Cystic Degeneration of Uterine Fibroid Mimicking a Malignant Uterine Neoplasm on MRI

International Journal of Medicine, 2013
Uterine leiomyomas or fibroids are the most common neoplasm of the uterus. These are commonly encountered in middle aged women in the reproductive age group. Depending upon the location within the uterus and their size, fibroids can be symptomatic or asymptomatic. The common symptoms are of abnormal vaginal bleeding and pain.
Pramod Philip Nittala, Roshni Shukla
openaire   +2 more sources

AAPM medical physics practice guideline 13.a: HDR brachytherapy, part B

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The goal of this report is to assist the clinical medical physicist in assuring that key quality standards and practice considerations are met to ensure safe, reliable, and reproducible high dose rate (HDR) brachytherapy (BT) treatment. This guideline has been developed to provide appropriate minimum standards for such services.
Susan L. Richardson, Arjit K. Baghwala, Gil'ad N. Cohen, Claire Dempsey, Bruce Libby, Christopher S. Melhus, Robin A. Miller, Daniel J. Scanderbeg, Samantha J. Simiele   +8 more
wiley   +1 more source

Conservative Treatment of Ewing’s Sarcoma of the Uterus in Young Women

Case Reports in Obstetrics and Gynecology, 2015
Ewing sarcoma-primitive neuroectodermal tumors (ES/PNETs) constitute a family of neoplasms characterized by a continuum of neuroectodermal differentiations. ES/PNET of the uterus is rare.
Giuseppe Loverro, Leonardo Resta, Edoardo Di Naro, Anna Maria Caringella, Salvatore Andrea Mastrolia, Mario Vicino, Massimo Tartagni, Luca Maria Schonauer   +7 more
doaj   +1 more source