Results 81 to 90 of about 598,872 (375)

A potential diagnostic biomarker: Proteasome LMP2/b1i-differential expression in human uterus neoplasm [PDF]

, 2012
Uterine leiomyosarcoma (ULMS) develops more often in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of uterine ULMS
Akiko Horiuchi, Hiroyuki Aburatani, Ikuo Konishi, Nobuo Yaegashi, Susumu Tonegawa, Takuma Hayashi   +5 more
core   +1 more source

Cervical, vaginal and vulvar intraepithelial neoplasms [PDF]

, 2011
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Mitrović-Jovanović Ana, Nikolić Branka, Pantić-Aksentijevic Snežana, Perišić Živko, Stanimirović Branko, Zamurović Milena   +5 more
core   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

Epithelioid trophoblastic tumor

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To describe a case of epithelioid trophoblastic tumor (ETT) in a postmenopausal woman, which had several peculiar features that differentiate it from previously reported ETTs.
Sevinc Hallac Keser, Sermin Coban Kokten, Caglar Cakir, Sibel Sensu, Esra Esim Buyukbayrak, Nimet Karadayi   +5 more
doaj   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Prognostic Factors for Survival in Patients with Carcinoma Endometrium

South Asian Journal of Cancer, 2022
Aparna Mullangath Prakasan Objective The study aimed to see the clinical outcome and to identify prognostic factors for survival in patients with carcinoma endometrium.
Aparna Mullangath Prakasan, Minolin Dhas, Krishnapillai M. Jagathnathkrishna, Aswin Kumar, Susan Mathews, John Joseph, Suchetha Sambasivan, Francis V. James   +7 more
doaj   +1 more source

Clear Cell Adenocarcinoma of Cervix: Radical Trachelectomy to Preserve the Fertility [PDF]

, 2016
Carcinoma of the uterine cervix is a common gynecologic malignant neoplasm all over the world. The most common histological type of malignant cervical neoplasms is squamous cell carcinoma [1,2].
Herraiz Roda, José Luis, Llueca, Antoni, Maazouzi, Yasmine, Medina, Carmen, Piquer Simó, Dolors   +4 more
core   +1 more source

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities [PDF]

, 2015
Background : Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for ...
Bosteels, Jan, Broekmans, Frank J, D'Hooghe, Thomas M, Kasius, Jenneke, Mol, Ben Willem J, Weyers, Steven   +5 more
core   +2 more sources

Surgery for Older Cancer Patients: Cross‐Organ Review and Good Practice Statement by the Japanese Geriatric Oncology Guideline Committee

Annals of Gastroenterological Surgery, EarlyView.
We conducted a cross‐organ review of surgical outcomes in older cancer patients based on literature cited in Japanese clinical guidelines. This study summarizes postoperative complication rates and survival outcomes across five major cancer types. The findings aim to support the development of geriatric oncology surgical guidelines tailored to Japan's ...
Chie Tanaka, Takashi Ofuchi, Kiichiro Ninomiya, Daisuke Inoue, Ken Sugimoto, Keiko Murofushi, Toru Okuyama, Shigeaki Watanuki, Chiyo Imamura, Daisuke Sakai, Naomi Sakurai, Kiyotaka Watanabe, Kazuo Tamura, Toshiaki Saeki, Hiroshi Ishiguro   +14 more
wiley   +1 more source

Endometrial Stromal Sarcoma Presenting As Puberty Menorrhagia [PDF]

, 2005
Endometrial stromal sarcomas are rare uterine tumours usually seen in perimenopausal females. We report here a case of low grade malignant endometrial stromal sarcoma in an adolescent girl, presenting as puberty menorrhagia.
Prabhakaran Nair, Rema, Sebastian, Paul
core   +1 more source