Results 91 to 100 of about 60,712 (301)
Utilitarianism, Degressive Proportionality and the Constitution of a Federal Assembly [PDF]
, 2005 A federal assembly consists of a number of representatives for each of the nations (states, Länder, cantons,...) that make up the federation. How many representatives should each nation receive?
Bovens, Luc, Hartmann, Stephan
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Case for Utilitarian Voting [PDF]
Utilitarian voting (UV) is defined in this paper as any voting rule that allows the voter to rank all of the alternatives by means of the scores permitted under a given voting scale. Specific UV rules that have been proposed are approval voting, allowing
Hillinger, Claude
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Step 6. Manipulating utilitarian judgment
, 2020 In this last step, our goal is to use the stimuli developed in the prior steps of our project to investigate the role of reflection in utilitarian judgments, outside of the particular case of moral dilemmas.
François Jaquet, Florian Cova
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Twofold Optimality of the Relative Utilitarian Bargaining Solution [PDF]
Given a bargaining problem, the `relative utilitarian' (RU) solution maximizes the sum total of the bargainer's utilities, after having first renormalized each utility function to range from zero to one. We show that RU is `optimal' in two very different
Pivato, Marcus
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Justifying Social Discounting: The Rank-Discounted Utilitarian Approach [PDF]
The discounted utilitarian criterion for infinite horizon social choice has been criticized for treating generations unequally. We propose an extended rank-discounted utilitarian (ERDU) criterion instead.
Geir B. Asheim, Stéphane Zuber
core
Asia Marketing Journal, 2013 During recent decades, the number of mixed attribute products (henceforth mixed products), which have both utilitarian and hedonic benefits, has increased dramatically.
You Jae Yi, Sun Hee Muhn
doaj +1 more source