Results 81 to 90 of about 246,445 (299)

Building castles in Spain: Peirce’s idea of scientific inquiry and its applications to the Social Sciences and to Ethics [PDF]

open access: yes, 2016
Several recent publications attest to a renewed interest, at the dawn of the 21st century, in the philosophy of Charles S. Peirce. While agreeing with the relevance of Peirce philosophy for the 21st century, we disagree with some interpretations of ...
Galanes Valldejuli, Luis, Nubiola, Jaime
core  

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Population Principles with Number-Dependent Critical Levels [PDF]

open access: yes
This paper introduces and characterizes the number-sensitive critical-level generalized utilitarian family of population principles which is a generalization of the critical-level generalized-utilitarian family.
Blackorby, Charles   +2 more
core  

The Ethics of Making Risky Decisions for Others [PDF]

open access: yes, 2019
Utilitarianism, it has been said, is not sensitive to the distribution of welfare. In making risky decisions for others there are multiple sensitivities at work.
Bovens, Luc
core  

Rawls versus utilitarianism: the subset objection [PDF]

open access: yes, 2016
This paper presents an objection to John Rawls’s use of the original position method to argue against implementing utilitarian rules. The use of this method is pointless because a small subset of the premises Rawls relies on can be used to infer the same
Goldman, Nozick, Rawls, Scheffler
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Reconciling utilitarian and non-utilitarian approaches to biodiversity conservation

open access: yesEthics in Science and Environmental Politics, 2014
Two broad types of approaches have been used in biodiversity conservation: (1) non-utilitarian approaches, which put the emphasis on the aesthetic, emotional, spiritual, and ethical values of nature, and (2) utilitarian approaches, which put the emphasis
M Loreau
doaj   +1 more source

A Defense of Scalar Utilitarianism [PDF]

open access: yes, 2017
Scalar Utilitarianism eschews foundational notions of rightness and wrongness in favor of evaluative comparisons of outcomes. I defend Scalar Utilitarianism from two critiques, the first against an argument for the thesis that Utilitarianism's ...
Tobia, Kevin Patrick
core  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

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