Results 101 to 110 of about 88,476 (300)

Risky mindset: prior exposure to risk increases utilitarian choices in sacrificial moral scenarios

Frontiers in Behavioral Economics
Evidence of cross-domain spillover into the moral domain has been limited to altruistic and consumption behaviors. Building on the literature on spillover effects and domain-general decision processes, we predicted that choice behavior in the economic ...
Abhishek Sahai, Jaison A. Manjaly
doaj   +1 more source

Regulatory fit and evaluation mode : feeling right about hedonic and utilitarian consumption [PDF]

, 2019
This research examines how regulatory focus affects the evaluation of hedonic and utilitarian attributes of products. My research found that promotion- focused people have higher evaluation of hedonic attributes over utilitarian attributes. The reverse was found for prevention focused subjects.
openaire   +3 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Utilitarian Mechanism Design for an Excludable Public Good [PDF]

This paper studies the design of optimal utilitarian mechanisms for an excludable public good. Excludability provides a basis for making people pay for admissions; the payments can be used for redistribution and/or funding.
Martin Hellwig
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Consumer Evaluation of Virtual vs. Human Influencers via Source Credibility, Perceived Social Similarity, and Consumption Motivation

Journal of Theoretical and Applied Electronic Commerce Research
Influencer marketing is estimated to reach USD 32.55 billion by the year 2025. The extant research on virtual vs. human influencers’ effectiveness has reported mixed results.
Huai-Kuan Zeng, Carolyn A. Lin
doaj   +1 more source

Exploring utilitarian and hedonic aspects of consumption at the Bottom of Pyramid

, 2017
O nmero de pesquisas sobre o Fundo da Pirmide aumentou nas ltimas dcadas; no entanto, uma discusso sobre seus hbitos de consumo ainda necessria. Assim, este trabalho tem como objetivo investigar o comportamento de consumidores em mercados informais, inerentes a esse segmento.
Gerhard, Felipe, Souza, Lucas Lopes Ferreira de, Peñaloza, Verónica, Denegri, Marianela   +3 more
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Examining the moderating effect of shopping value on private-label and loyalty in Indian grocery stores

Management şi Marketing, 2018
The present study has attempted to create and examine a conceptually grounded working model that examines the moderating influence of utilitarian and hedonic shopping values with Indian grocery stores on the association between usage of Private Label (PL)
Bhat Ishfaq Hussain, Singh Sapna
doaj   +1 more source