Results 111 to 120 of about 3,565,302 (299)
Foundations of continuous-time recursive utility : differentiability and normalization of certainty equivalents [PDF]
, 2009 This paper relates recursive utility in continuous time to its discrete-time origins and provides a rigorous and intuitive alternative to a heuristic approach presented in [Duffie, Epstein 1992], who formally define recursive utility in continuous time ...
Kraft, Holger, Seifried, Frank Thomas
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Firebird Database Backup by Serialized Database Table Dump [PDF]
, 2007 This paper presents a simple data dump and load utility for Firebird databases which mimics mysqldump in MySQL. This utility, fb_dump and fb_load, for dumping and loading respectively, retrieves each database table using kinterbasdb and serializes the ...
Ling, Maurice HT
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
GREEN MARKETING AND SUSTAINABLE DEVELOPMENT – EXPERIENCES FROM REPUBLIC OF SERBIA
Journal of Economic Development, Environment and People, 2012 The world must be developed according to the needs of people, but with the obligation of sustainable development as a comprehensive process that depress all aspects of life, at all levels.
Radnovic Branislav +2 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Fundamental flaws in the current cost regulatory capital value method of utility pricing [PDF]
, 2007 Jim Cuthbert and Margaret Cuthbert’s most recent analysis of the UK’s utility businesses (see QEC Vol 31 No 3) seeks to challenge the fundamental price setting methodology adopted by utility regulators.
Armstrong, Jo
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Risk, ambiguity and quantum decision theory
, 2007 In the present article we use the quantum formalism to describe the effects of risk and ambiguity in decision theory. The main idea is that the probabilities in the classic theory of expected utility are estimated probabilities, and thus do not follow ...
Aerts +20 more
core +1 more source