Results 161 to 170 of about 1,775,789 (317)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Capacity utilization and market power. [PDF]

In a monopolistic competition framework, we propose a dynamic model in which capacity underutilization is a macroeconomic equilibrium feature relying on a diversity of microeconomic situations.
Licandro, Omar, Fagnart, Jean-Francois, Sneessens, Henri   +2 more
core  

Mental health service utilization among people with intellectual and developmental disabilities and serious mental illness before and during the emergence of telehealth services. [PDF]

Front Health Serv
Lauer E, Howland RE, Royer J, Hall JP, Kurth NK, Hunt SL, Walter D, Neighbors CJ, McDermott SW.   +8 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Fabrication technology.

Issued as part of the Technology Utilization Program.Mode of access ...
United States. National Aeronautics and Space Administration. Technology Utilization Office.
core  

A national-wide analysis of dental services utilization in primary health care settings in rural areas of Iran. [PDF]

J Educ Health Promot
Pouraghasi L, Olyaeemanesh A, Nouhi M, Jafari M.   +3 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Exploring the contribution of straw utilization to carbon emission reduction in Anhui Province (China). [PDF]

PLoS One
Ye Z, Yu X, Yao R, Yao Y.
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

utilization of bioremediation to reduce soil contamination: problems and solutions

edited by Va?clav S?as?ek, John A. Glaser and Philippe Baveye.xix, 417 p. : ill.
Baveye, P. (Philippe), North Atlantic Treaty Organization, Glaser, John A., NATO Advanced Research Workshop on the Utilization of Bioremediation to Reduce Soil Contamination: P, S?as?ek, Va?clav.   +4 more
core