Results 91 to 100 of about 469,896 (294)

Gradient-based Reinforcement Planning in Policy-Search Methods

open access: yes, 2001
We introduce a learning method called ``gradient-based reinforcement planning'' (GREP). Unlike traditional DP methods that improve their policy backwards in time, GREP is a gradient-based method that plans ahead and improves its policy before it actually
Hutter, Marcus   +2 more
core   +1 more source

Forty hours of declarative programming: Teaching Prolog at the Junior College Utrecht

open access: yes, 2013
This paper documents our experience using declarative languages to give secondary school students a first taste of Computer Science. The course aims to teach students a bit about programming in Prolog, but also exposes them to important Computer Science ...
Stutterheim, Jurriën   +2 more
core   +2 more sources

Unlocking Heterobimetallic Architectures in a Symmetric PNNP Ligand Environment

open access: yesChemistry – A European Journal, EarlyView.
A symmetric PNNP ligand enables the modular assembly of heterobimetallic ZnRu and CoRu complexes from a mononuclear Ru(II) precursor. Ligand deprotonation triggers dearomatization and contraction of the metal–metal distance. Combined DFT and QTAIM analyses reveal metallophilic interaction in CoRu but not in ZnRu, highlighting controllable geometric and
Stanislav Melnikov   +4 more
wiley   +1 more source

An Answer Explanation Model for Probabilistic Database Queries [PDF]

open access: yes, 2007
Following the availability of huge amounts of uncertain data, coming from diverse ranges of applications such as sensors, machine learning or mining approaches, information extraction and integration, etc.
Apers, Peter M.G.   +3 more
core   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of 5‐HT3 Receptor Antagonists: 2026 Update

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
5‐hydroxytryptamine type 3 (5‐HT3) receptor antagonists are used to treat nausea and vomiting and in the prevention of chemotherapy‐induced, radiation‐induced, and postoperative nausea and vomiting. Most of the 5‐HT3 receptor antagonists (i.e., ondansetron, tropisetron, dolasetron, palonosetron, and ramosetron) are metabolized by CYP2D6, but the extent
Claire Moore   +16 more
wiley   +1 more source

Thymic NK-Cells and Their Potential in Cancer Immunotherapy

open access: yesImmunoTargets and Therapy
Caitlyn Forbes,1 Stefan Nierkens,1,2,* Annelisa M Cornel1,2,* 1Princess Máxima Center for Pediatric Oncology, Utrecht University, Utrecht, the Netherlands; 2Center for Translational Immunology, University Medical Center Utrecht, Utrecht ...
Forbes C, Nierkens S, Cornel AM
doaj  

Alcohol mixed with energy drinks: methodology and design of the Utrecht Student Survey

open access: yesInternational Journal of General Medicine, 2012
Lydia de Haan,1 Hein A de Haan,2,3 Berend Olivier,1 Joris C Verster11Utrecht University, Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacology, Utrecht, The Netherlands; 2Tactus Addiction Treatment, Deventer, The Netherlands; 3Nijmegen ...
de Haan L   +3 more
doaj  

The Quest for Stability: The View of Financial Institutions

open access: yes, 2010
On September 3-4, 2009 SUERF and Utrecht University School of Economicsorganized the Colloquium "The Quest for Stability" in Utrecht, the Netherlands.
Blommestein, Hans J.   +6 more
core  

Artificial Intelligence for Regulatory Evidence: A Systematic Document Analysis of European Medicines Agency Regulatory Advice and Public Reports

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Artificial intelligence (AI) is receiving increasing attention across the entire lifecycle of medicines, from early development to postauthorization use. While various AI tools have been developed in commercial and academic settings, the extent of their use in regulatory contexts within the European Union remains unknown.
Lucina‐May Nollen   +3 more
wiley   +1 more source

Evaluación del compromiso estudiantil en un grupo de ciencias de la actividad física y salud

open access: yesRECUS, 2017
Con el propósito de valorar los niveles de dedicación, energía y absorción en estudiantes de Guanajuato, México, se aplicó la Escala Utrecht de Engagement (UWES) a 40 alumnos de Ciencias de la Actividad Física y Salud. El coeficiente Alfa de Cronbach de .
Lucía Rodríguez Guzmán   +1 more
doaj  

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