Results 111 to 120 of about 468,025 (232)

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

open access: yesEpilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe   +5 more
wiley   +1 more source

Ultra-compact binaries: relevance and role of Utrecht [PDF]

open access: yes, 2012
We present a short overview of the formation and evolution of ultra-compact binaries. They are relevant to a surprisingly large number of astrophysical phenomena (binary interactions, mass transfer stability, explosive phenomena such as type Ia ...
Nelemans, G., van Haaften, L.
core   +1 more source

Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis: A shared phenotype across brain‐expressed sodium channelopathies

open access: yesEpilepsia, EarlyView.
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli   +43 more
wiley   +1 more source

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas   +11 more
wiley   +1 more source

Clinical utility of asthma biomarkers: from bench to bedside

open access: yesBiologics: Targets & Therapy, 2013
Susanne JH Vijverberg,1,2,* Bart Hilvering,2,* Jan AM Raaijmakers,1 Jan-Willem J Lammers,2 Anke-Hilse Maitland-van der Zee,1,* Leo Koenderman2,* 1Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences ...
Vijverberg SJH   +5 more
doaj  

Historical geomagnetic observations from the Netherlands during the Carrington event (1859)

open access: yesJournal of Space Weather and Space Climate
The Carrington event of September 1859 is the best known example of an extreme geomagnetic storm, often cited when discussing space weather risks for modern infrastructure.
van Dam K.   +3 more
doaj   +1 more source

Stand Up, Speak Out: Stimulating Dissent in Social Justice Teacher Education

open access: yesFuture in Educational Research, EarlyView.
ABSTRACT Teacher education should not only prepare student teachers for their role in the existing educational system but also equip them to critically question and reform that system when confronted with injustice. We advocate for dissent in the future of teacher education.
Koen Hoondert   +4 more
wiley   +1 more source

Sustainable and accessible hemodialysis: life cycle assessment on central acid delivery system

open access: yesBMC Nephrology
Introduction The healthcare sector contributes over 4% of global greenhouse gas emissions. As healthcare systems pursue carbon reduction targets, sustainable innovations in clinical operations are essential.
Chang-Lung Tsai   +5 more
doaj   +1 more source

Limited Sensitivity of Ultrasound‐Guided Fine‐Needle Aspiration Cytology for Occult Nodal Metastases in Early‐Stage Oral Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Ultrasound‐guided fine‐needle aspiration cytology (US‐FNAC) is commonly used in the diagnostic work‐up of head and neck cancer, but its ability to detect occult lymph node metastases in early‐stage oral squamous cell carcinoma (OSCC) with a clinically negative neck remains unclear.
Dominique N. V. Donders   +7 more
wiley   +1 more source

Experimental treatment of Quark and Gluon Jets

open access: yes, 2011
The separate study of quark and gluon jets is vital for the interpretation of multiple variables behaviour observed in both high-energy hadron and heavy-ion collisions in the present and future experiments.
Pochybova, Sona
core  

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