Results 61 to 70 of about 468,025 (232)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Boekbespreking van C. Nas, ‘EQUIPping’ delinquent male adolescents to think pro-socially [PDF]

, 2006
Bespreking (review) van: Coralijn Nas, ‘EQUIPping’ delinquent male adolescents to think pro-socially (diss.
Veenstra, René
core  

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma

International Journal of Nanomedicine, 2018
Maaike VJ Braham,1 Anil K Deshantri,2,3 Monique C Minnema,4 F Cumhur Öner,1 Raymond M Schiffelers,2 Marcel HAM Fens,2,5 Jacqueline Alblas1 1Department of Orthopaedics, University Medical Center Utrecht, Utrecht, the Netherlands; 2Department of ...
Braham MVJ, Deshantri AK, Minnema MC, Öner FC, Schiffelers RM, Fens MHAM, Alblas J   +6 more
doaj  

Prevalence and Predictors of Uncontrolled Asthma in Children Referred for Asthma and Other Atopic Diseases

Journal of Asthma and Allergy, 2020
HM Kansen,1,2 TM Le,2 CSPM Uiterwaal,3 BE van Ewijk,4 WAF Balemans,5 DMW Gorissen,6 E de Vries,7 MF van Velzen,8 GHPR Slabbers,9 Y Meijer,1 AC Knulst,2 CK van der Ent,1 FC van Erp2 1Department of Pediatric Pulmonology and Allergology, Wilhelmina Children&
Kansen HM, Le TM, Uiterwaal CSPM, van Ewijk BE, Balemans WAF, Gorissen DMW, de Vries E, van Velzen MF, Slabbers GHPR, Meijer Y, Knulst AC, van der Ent CK, van Erp FC   +12 more
doaj  

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

IDENTIDAD URBANA Y EL TURISMO DE EVENTOS DEPORTIVOS: EL GRAND DEPART TOUR DE FRANCIA 2015

Cuadernos de Turismo, 2017
Ciudades de todo tipo en la actual jerarquía urbana se afanan por adquirir una nueva identidad. En ese proceso de reinvención urbana, el turismo de eventos deportivos ha venido desarrollando una gran capacidad para generar diferentes impactos ‘tangibles’
Juan Luis Paramio-Salcines, Roberto Ruiz Barquín, Manuel Jesús Baena Arroyo   +2 more
doaj   +3 more sources

A method to incorporate interstitial components into the TPS gynecologic rigid applicator library

Journal of Contemporary Brachytherapy, 2017
Purpose: T2 magnetic resonance imaging (MRI) is recommended as the imaging modality for image-guided brachytherapy. In locally advanced cervical carcinoma, combined endocavitary and interstitial applicators are appropriate (Vienna or Utrecht). To cover
Antonio Otal, Jose Richart, Silvia Rodriguez, Manuel Santos, Jose Perez-Calatayud   +4 more
doaj   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Las aguas de Gibraltar, el Tratado de Utrecht y el Derecho Internacional del Mar

Cuadernos de Gibraltar, 2015
I.- CONSIDERACIONES INICIALES – II. UN TRATADO Y DOS LECTURAS: UTRECHT – III. EL TRATADO DE UTRECHT Y LAS AGUAS ADYACENTES AL PEÑÓN DE GIBRALTAR – IV.
Jesús Verdú Baeza
doaj