Subcutaneous injection, from birth, of epigallocatechin-3-gallate, a component of green tea, limits the onset of muscular dystrophy in mdx mice: a quantitative histological, immunohistochemical and electrophysiological study [PDF]
, 2018 Dystrophic muscles suffer from enhanced oxidative stress. We have investigated whether administration of an antioxidant, epigallocatechin-3-gallate (EGCG), a component of green tea, reduces their oxidative stress and pathophysiology in mdx mice, a mild ...
Goto, Junpei +6 more
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The potential of utrophin modulators for the treatment of Duchenne muscular dystrophy [PDF]
, 2018 Simon Guiraud +2 more
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Washington University Record, October 30, 1997 [PDF]
, 1997 https://digitalcommons.wustl.edu/record/1773/thumbnail ...
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Systemic investigation of bone and muscle abnormalities in dystrophin/utrophin double knockout mice during postnatal development and the mechanisms [PDF]
, 2019 Xueqin Gao +7 more
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Utrophin upregulation in Duchenne muscular dystrophy.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2006 Duchenne Muscular Dystrophy (DMD) is a devastating, progressive muscle wasting disease for which there is currently no effective treatment. DMD is caused by mutations in the dystrophin gene many of which result in the absence of the large cytoskeletal protein dystrophin at the sarcolemma.
Hirst, R, McCullagh, K, Davies, K
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Utrophin Is a Regeneration-associated Protein Transiently Present at the Sarcolemma of Regenerating Skeletal Muscle Fibers in Dystrophin-deficient Hypertrophic Feline Muscular Dystrophy [PDF]
, 1998 Shuo Lin +2 more
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Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes [PDF]
, 2017 In eukaryotic cells, transgene expression levels may be limited by an unfavourable chromatin structure at the integration site. Epigenetic regulators are DNA sequences which may protect transgenes from such position effect.
Aritonovska, Elena +2 more
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Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD [PDF]
, 2022 Britt Hanson +8 more
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Exercise Increases Utrophin Protein Expression in the MDX Mouse Model of Duchenne Muscular Dystrophy [PDF]
, 2013 Please view abstract in the attached PDF ...
Gordon, B. S. +2 more
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