Results 141 to 150 of about 7,799 (249)

Novel Adeno‐Associated Viral Vector Delivering the Utrophin Gene Regulator Jazz Counteracts Dystrophic Pathology in mdx Mice

, 2014
Georgios Strimpakos, Nicoletta Corbi, Cinzia Pisani, Maria Grazia Di Certo, Annalisa Onori, Siro Luvisetto, Cinzia Severini, Francesca Gabanella, Lucia Monaco, Elisabetta Mattei, Claudio Passananti   +10 more
openalex   +1 more source

Utrophin ABD binds to F‐actin in an open conformation

, 2012
Mike J.F. Broderick, Andrey A. Bobkov, Steve J. Winder   +2 more
openalex   +1 more source

Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes [PDF]

, 2017
In eukaryotic cells, transgene expression levels may be limited by an unfavourable chromatin structure at the integration site. Epigenetic regulators are DNA sequences which may protect transgenes from such position effect.
Aritonovska, Elena, Majocchi, Stefano, Mermod, Nicolas   +2 more
core  

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue [PDF]

, 2018
.: The dystrophin glycoprotein complex (DGC) is a multimeric protein assembly associated with either the X-linked cytoskeletal protein dystrophin or its autosomal homologue utrophin. In striated muscle cells, the DGC links the extracellular matrix to the
Fritschy, J., Haenggi, T.
core  

The potential of utrophin modulators for the treatment of Duchenne muscular dystrophy [PDF]

, 2018
Simon Guiraud, David Roblin, Davies. E. Kay   +2 more
openalex   +1 more source

Exercise Increases Utrophin Protein Expression in the MDX Mouse Model of Duchenne Muscular Dystrophy [PDF]

, 2013
Please view abstract in the attached PDF ...
Gordon, B. S., Kostek, M. C., Lowe, D. A.   +2 more
core   +1 more source

2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy

, 2020
Arran Babbs, Adam Berg, Maria Chatzopoulou, Kay E. Davies, Stephen G. Davies, Benjamin Edwards, David J. Elsey, Enrico Emer, Simon Guiraud, Shawn Harriman, Cristina Lecci, Lee Moir, David G. Peters, Neil Robinson, Jessica A. Rowley, Angela J. Russell, Sarah Squire, Jonathon M. Tinsley, Francis X. Wilson, Graham M. Wynne   +19 more
openalex   +1 more source

Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice

, 2009
Santhosh M. Baby, Sasha Bogdanovich, Gabriel Willmann, Utpal Basu, Olga Lozynska, Tejvir S. Khurana   +5 more
openalex   +2 more sources

Utrophin Is a Regeneration-associated Protein Transiently Present at the Sarcolemma of Regenerating Skeletal Muscle Fibers in Dystrophin-deficient Hypertrophic Feline Muscular Dystrophy [PDF]

, 1998
Shuo Lin, Frédéric Gaschen, J‐M. Burgunder   +2 more
openalex   +1 more source

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD [PDF]

, 2022
Britt Hanson, Sofia Stenler, Nina Ahlskog, Katarzyna Chwalenia, Nenad Svrzikapa, Anna Coenen-Stass, Marc S. Weinberg, Matthew J. A. Wood, Thomas C. Roberts   +8 more
openalex   +1 more source