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Understanding the endothelial function of utrophin.
, 2016 Ehmsen, J, Weir, A, Davies, K
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Complex transcription of the utrophin gene: A study of short utrophin isoforms
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The Optic cup is actively shape programmed by independently patterned apical forces
Ramos AP +6 more
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Nature Genetics, 1998
Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease usually resulting in death of patients by their early twenties. In contrast, mice lacking dystrophin (Dmd(mdx)), appear physically normal despite their underlying muscle pathology.
Jeffrey S Chamberlain
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Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease usually resulting in death of patients by their early twenties. In contrast, mice lacking dystrophin (Dmd(mdx)), appear physically normal despite their underlying muscle pathology.
Jeffrey S Chamberlain
exaly +3 more sources
Downstream utrophin enhancer is required for expression of utrophin in skeletal muscle
The Journal of Gene Medicine, 2008AbstractBackgroundDuchenne muscular dystrophy is caused by the absence of the muscle cytoskeletal protein dystrophin. Utrophin is an autosomal homologue of dystrophin, and overexpression of utrophin is expected to compensate for the dystrophin deficit.
Jun, Tanihata +4 more
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A study of short utrophin isoforms in mice deficient for full-length utrophin
Mammalian Genome, 2003Utrophin can functionally replace dystrophin in dystrophin-deficient muscle and may have a role in a therapeutic strategy for Duchenne muscular dystrophy. This has resulted in many investigations of the full-length muscle form of utrophin; however, the short utrophins and non-muscle forms have been relatively neglected, partly because they are ...
Jimenez-Mallebrera C +3 more
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