Results 81 to 90 of about 7,866 (244)
FEBS Letters, Volume 599, Issue 20, Page 2878-2895, October 2025.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
l-arginine improves dystrophic phenotype in mdx mice
Neurobiology of Disease, 2005 A possible treatment for Duchenne muscular dystrophies would be to compensate for dystrophin loss by increasing the expression of utrophin, another cytoskeletal protein of the muscle membrane. We previously found that l-arginine, the substrate for nitric
Vincent Voisin +7 more
doaj +1 more source
Visualization of actin filaments and monomers in somatic cell nuclei [PDF]
, 2013 © The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Molecular Biology of the Cell 24 (2013): 982-994, doi:10.1091/mbc.E12-09-0685.In addition to its long-
Belin, Brittany J. +3 more
core +1 more source
Cloning and expression of full length mouse utrophin: the differential association of utrophin and dystrophin with AChR clusters [PDF]
FEBS Letters, 1996 We have cloned and sequenced mouse utrophin cDNA, and successfully expressed full length utrophin (400 kDa) in both muscle and non‐muscle cells. The expression of recombinant utrophin is compared with that of its homologue, dystrophin (427 kDa). We demonstrate that recombinant utrophin is targeted into agrin‐induced acetylcholine receptor (AChR ...
Athena Guo, W.-X. +2 more
openaire +2 more sources
Developmental Dynamics, Volume 254, Issue 10, Page 1115-1132, October 2025.Abstract Background The forces underlying convergence and internalization of the teleost neural plate remain unknown. To help understand this morphogenesis, we analyzed collective and individual cell behaviors at the superficial surface of the neural plate as internalization begins to form the neural keel in the hindbrain region of the zebrafish embryo.
Claudio Araya +11 more
wiley +1 more source
Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice [PDF]
, 2017 Aims Duchenne muscular dystrophy (DMD) is a severe striated muscle disease due to the absence of dystrophin. Dystrophin deficiency results in dysfunctional sodium channels and conduction abnormalities in hearts of mdx mice. Disease progression in the mdx
Abriel, Hugues +3 more
core
Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]
, 2015 A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding +8 more
core +1 more source
Expression of the utrophin gene during myogenic differentiation [PDF]
Nucleic Acids Research, 1999 The process of myogenic differentiation is known to be accompanied by large increases ( approximately 10-fold) in the expression of genes encoding cytoskeletal and membrane proteins including dystrophin and the acetylcholine receptor (AChR) subunits, via the effects of transcription factors belonging to the MyoD family.
A O, Gramolini, B J, Jasmin
openaire +2 more sources
The FEBS Journal, Volume 292, Issue 19, Page 5067-5085, October 2025.Duchenne muscular dystrophy is a severe neuromuscular wasting disease that is caused by a primary defect in dystrophin protein. A targeted mass‐spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy.
Erynn E. Johnson, James M. Ervasti
wiley +1 more source
Identification of new dystroglycan complexes in skeletal muscle. [PDF]
PLoS ONE, 2013 The dystroglycan complex contains the transmembrane protein β-dystroglycan and its interacting extracellular mucin-like protein α-dystroglycan. In skeletal muscle fibers, the dystroglycan complex plays an important structural role by linking the ...
Eric K Johnson +6 more
doaj +1 more source