Results 51 to 60 of about 2,690,211 (327)

Rapid preparative isolation of cleistanthin A from the leaves of Cleistanthus collinus Using reverse-phase flash chromatography

open access: yesJournal of Pharmacy and Bioallied Sciences, 2022
Introduction: Cleistanthin A (CA) is an aryl naphthalene lignan, which has a potent anticancer activity by regulating the tumor microenvironment. The objective was to develop a new technique for the isolation of cleistanthin A from the acetone extract of
S C Santosh Kumar   +2 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

UV or Not UV: Metals Are The Answer [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2008
Advances in our understanding of the etiology of cutaneous melanoma over the past decade have implicated constitutive heredity alterations in a small percentage of cases (5-8%). Using the power of competitive genomic hybridization, melanomas located in intermittently sun exposed areas have ...
Meyskens, Frank L, Jr, Berwick, Marianne
openaire   +3 more sources

Rocket-UV Spectrometer [PDF]

open access: yes, 1961
This is a report of the second three months (March-May 1961) of a program to design and fabricate an ultraviolet spectrometer and fine guidance control for use in an Aerobee-Hi rocket. The work is being done under Subcontract No.
Burgess, Julian, Westberg, Karl
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

IDENTIFICATION OF LECTINS OF ZEA MAYS RAW MATERIAL AND THE STUDY OF LECTIN ACTIVITY [PDF]

open access: yesAnnals of Mechnikov's Institute, 2013
The aime of the study was to identify lectins in the Zea mays raw material: roots, stems, heads, leaves and corn silk and study their activity. Lectins activity has been studied using the biological method of ratuserytroagglutination.
Karpiuk UV, Kyslychenko VS
doaj  

Another Faint UV Object Associated with a Globular Cluster X-Ray Source: The Case of M92

open access: yes, 2000
The core of the metal poor Galactic Globular Cluster M92 (NGC 6341) has been observed with WFPC2 on the Hubble Space Telescope through visual, blue and mid-UV filters in a program devoted to study the evolved stellar population in a selected sample of ...
Barbara Paltrinieri   +18 more
core   +1 more source

Frequency stabilization of an ultraviolet semiconductor disk laser [PDF]

open access: yes, 2013
We report a tunable, narrow-linewidth UV laser based on intracavity second-harmonic generation in a red semiconductor disk laser. Single-frequency operation is demonstrated with a total UV output power of 26 mW. By servo-locking the fundamental frequency
Hastie, Jennifer   +2 more
core   +1 more source

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