Results 61 to 70 of about 10,248,710 (343)

Enhancing performance of Ag–ZnO–Ag UV photodetector by piezo-phototronic effect

open access: yesRSC Advances, 2018
An ultraviolet photodetector based on a ZnO nanowires with metal–semiconductor–metal Schottky structure was fabricated on a flexible polyester fibre substrate.
Xiaotong Zhang   +5 more
openaire   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Differences in aroma quality of cold-steamed jujube brandy with different aging methods [PDF]

open access: yesZhongguo niangzao
Using Xinjiang Jun-jujube as raw material, the jujube brandy was produced by low-temperature distillation (≤70 ℃) technology. The effect of different aging methods (natural aging, UV-accelerated aging, and microwave-accelerated aging) on the aroma ...
FANG Qiang, FENG Zuoshan, BAI Yujia, SHI Qingheng, CUI Yuxin, ZHAO Yunfei, XU Xiangrong
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Study on Ultraviolet Aging Performance of Composite Modified Asphalt Based on Rheological Properties and Molecular Dynamics Simulation

open access: yesAdvances in Materials Science and Engineering, 2022
In order to study the effect of UV aging on asphalt performance, the asphalt four-component test, dynamic shear rheology test, and flexural creep stiffness test were combined with molecular dynamics simulation to matrix asphalt and rubber powder/styrene ...
Mingxing Gao   +3 more
doaj   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

Photochemical and ozone-induced aging significantly alter the viscosity of aqueous trans-aconitic acid aerosol particles [PDF]

open access: yesAtmospheric Chemistry and Physics
Aging processes of organic aerosols, including reactions with gas phase oxidants, such as ozone (O3), as well as photochemical reactions, can significantly alter their physicochemical properties.
C. Antossian   +3 more
doaj   +1 more source

Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers. [PDF]

open access: yes, 2012
BackgroundCigarette smoking is well-known to associate with accelerated skin aging as well as cardiovascular disease and lung cancer, in large part due to oxidative stress.
Beebe, Kirk D   +10 more
core   +4 more sources

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer   +3 more
wiley   +1 more source

Mucocutaneous disease activity and damage accrual in systemic lupus erythematosus: analyses from the Asia‐Pacific Lupus Collaboration longitudinal cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective This research article aims to describe the prevalence, associations and health‐related quality‐of‐life (HRQoL) impact of mucocutaneous features of SLE. Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analysed (2013‐2021). Mucocutaneous activity (MC‐A) items were rash, alopecia and mucosal ulcers; defined by the SLEDAI‐2K ...
Amanda M Saracino   +42 more
wiley   +1 more source

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