Results 31 to 40 of about 193,735 (267)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Balancing the solar irradiance needs: optimising growth in sphagnum palustre through tailored UV-B effects

BMC Plant Biology
Background The carbon sequestration potential and water retention capacity of peatlands are closely linked to the growth dynamics of Sphagnum mosses. However, few studies have focused on the response of Sphagnum moss growth dynamics to UV-B radiation ...
JiaYue Sun, Ling Xu, Lian Liu, BeiBei Huang, XingYu Liu, JunFeng Xu, Lin Wu   +6 more
doaj   +1 more source

Metabolomic Analysis of Elymus sibiricus Exposed to UV-B Radiation Stress

Molecules
Plants cultivated on the Qinghai-Tibet Plateau (QTP) are exposed to high ultraviolet radiation intensities, so they require effective mechanisms to adapt to these stress conditions.
Fei Zhang, Ming Sun, Daxu Li, Minghong You, Jiajun Yan, Shiqie Bai   +5 more
doaj   +1 more source

UV radiation increases phenolic compound protection but decreases reproduction in Silene littorea.

PLoS ONE, 2020
Plants respond to changes in ultraviolet (UV) radiation both morphologically and physiologically. Among the variety of plant UV-responses, the synthesis of UV-absorbing flavonoids constitutes an effective non-enzymatic mechanism to mitigate ...
José Carlos Del Valle, Mª Luisa Buide, Justen B Whittall, Fernando Valladares, Eduardo Narbona   +4 more
doaj   +1 more source

UV Radiation Induces Specific Changes in the Carotenoid Profile of Arabidopsis thaliana

Biomolecules, 2022
UV-B and UV-A radiation are natural components of solar radiation that can cause plant stress, as well as induce a range of acclimatory responses mediated by photoreceptors.
Uthman O. Badmus, Gaia Crestani, Natalie Cunningham, Michel Havaux, Otmar Urban, Marcel A. K. Jansen   +5 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Effects of radiation patterns from ultraviolet light-emitting diodes on the uniformity of the radiation field in surface disinfection

Fushe yanjiu yu fushe gongyi xuebao
When ultraviolet light-emitting diodes (UV-LEDs) are used for surface disinfection, the UV dose in some areas may exceed the required level but be insufficient in other areas.
YAO Sen, JIANG Yiqing, ZHANG Lianxi, ZHANG Lianfeng, TONG Zhangfa   +4 more
doaj   +1 more source

A VARIAÇÃO SAZONAL DA RADIAÇÃO ULTRAVIOLETA SOLAR BIOLOGICAMENTE ATIVA

Brazilian Journal of Geophysics, 2000
Séries temporais de radiação UV-B, biologicamente ativa, obtidas em vários locais no Brasil, em Punta Arenas no Chile e em La Paz na Bolívia são apresentadas.
V.W.J.H. Kirchhoff, E. Echer, N. P. Leme, A. A. Silva   +3 more
doaj   +1 more source

Ultraviolet-B radiation induces cell death in root tips and reprograms metabolism in Arabidopsis

Biologia Plantarum, 2020
Ultraviolet-B (UV-B) radiation inhibits root system growth, however, the influence of UV-B radiation on the regulation of root development remains unclear.
P. ZHANG, R. WANG, Y. WANG, J. XU
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source