Results 31 to 40 of about 30,180 (299)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

EFFECT OF UV IRRADIATION ON THE DYEING OF COTTON FABRIC WITH REACTIVE BLUE 204 [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2017
Reactive dyes are synthetic organic compounds used on a wide scale in textile industry, for painting materials of different types and compositions (e.g. 100% cotton, wool, natural satin, viscose, synthetic fibres).
ROŞU Liliana   +3 more
doaj  

A spectrally bright wavelength-switchable vacuum ultraviolet source driven by quantum coherence in strong-field-ionized molecules

open access: yesNew Journal of Physics, 2021
We report generation of spectrally bright vacuum ultraviolet (VUV) and deep UV (DUV) coherent radiations at the wavelengths of 192 nm, 198 nm and 204 nm.
Yuexin Wan   +8 more
doaj   +1 more source

Correlation, entropy, and information transfer in black hole radiation

open access: yes, 2014
Since the discovery of Hawking radiation, its consistency with quantum theory has been widely questioned. In the widely described picture, irrespective of what initial state a black hole starts with before collapsing, it eventually evolves into a thermal
Cai, Qingyu   +3 more
core   +1 more source

Generalized Vaidya Solutions and Misner-Sharp mass for $n$-dimensional massive gravity [PDF]

open access: yes, 2017
Dynamical solutions are always of interest to people in gravity theories. We derive a series of generalized Vaidya solutions in the $n$-dimensional de Rham-Gabadadze-Tolley (dRGT) massive gravity with a singular reference metric.
Hu, Ya-Peng   +2 more
core   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Effects of Gamma Ray Bursts in Earth Biosphere

open access: yes, 2009
We continue former work on the modeling of potential effects of Gamma Ray Bursts on Phanerozoic Earth. We focus on global biospheric effects of ozone depletion and show a first modeling of the spectral reduction of light by NO2 formed in the stratosphere.
B. Thomas   +12 more
core   +1 more source

Localized ultraviolet laser microbeam irradiation of early Drosophila embryos: Fate maps based on location and frequency of adult defects [PDF]

open access: yes, 1979
Drosophila embryos were locally irradiated with a 257-nm laser microbeam during blastoderm and germ band stages. Depending on stage and beam diameter (10–30 μm), from 0 to 45 nuclei were exposed to the uv radiation.
Cremer, Christoph   +4 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Resistance to Extreme Stresses by a Newly Discovered Japanese Tardigrade Species, Macrobiotus kyoukenus (Eutardigrada, Macrobiotidae)

open access: yesInsects, 2022
Tardigrades are small micrometazoans able to resist several environmental stresses in any stage of their life cycle. An integrated analysis of tardigrade specimens collected in Tsukuba (Japan) revealed a peculiar morphology and a new sensory field in the
Michele Cesari   +6 more
doaj   +1 more source

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