Results 21 to 30 of about 56,940 (172)

Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany

Arthritis Research & Therapy, 2020
Background To analyze whether ANA-positive idiopathic anterior uveitis differs from JIA-associated uveitis concerning clinical course, response to treatment, and disease outcome.
Arnd Heiligenhaus, Jens Klotsche, Martina Niewerth, Gerd Horneff, Gerd Ganser, Johannes-Peter Haas, Kirsten Minden   +6 more
doaj   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Evaluación de los cebadores TS3 e ITS4 para la detección de infecciones por Candida spp. en muestras de flujo vaginal y humor acuoso Evaluation of ITS3 and ITS4 primers for detection of Candida spp. Candida spp. infections from vaginal samples and aqueous humor

Infectio, 2008
Antecedentes. Los métodos convencionales para a identificación de levaduras del género Candida requieren mucho tiempo, necesitan cantidad importante de la muestra y, en muchos casos, es necesario realizar cultivo. Objetivos.
Juan Felipe Ramirez, Alejandra de la Torre   +1 more
doaj  

Más allá del intestino: manifestaciones extraintestinales de la enfermedad inflamatoria intestinal en niños y adolescentes

Revista Colombiana de Gastroenterología
Antecedentes: las manifestaciones extraintestinales (MEI) son comunes en niños y adultos y su presencia se asocia con mayor gravedad en la enfermedad inflamatoria intestinal (EII).
Angie Vanessa Vergara Espitia, Diana Victoria Mora Quintero, Jose Antonio De la Hoz Valle, Ana Maria Castañeda Figueroa, Fernando Sarmiento Quintero   +4 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Focos sépticos bucales en pacientes con uveítis Oral sepsis in patients with uveitis

Medisan, 2012
Se realizó un estudio descriptivo y transversal de 26 pacientes con uveítis, atendidos en el Servicio de Estomatología del Hospital General Docente "Juan Bruno Zayas Alfonso" de Santiago de Cuba, desde mayo hasta diciembre del 2011, con vistas a ...
Maritza Peña Sisto, Liliana Peña Sisto, Milagros Calzado de Silva, Yamilka Rodríguez Alonso, Lissette Santos Toled   +4 more
doaj  

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Enfermedad de Behçet asociada a trombosis venosa

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2019
La enfermedad de Behçet es una enfermedad crónica y multisistémica, caracterizada por uveítis, úlceras orales y úlceras genitales recurrentes. Se reporta un paciente con enfermedad de Behçet asociada a trombosis venosa profunda, que presentó edema en la
Yury Alexander Usuga, Gloria Andrea Vargas, Margarita María Velásquez, Luis Alfonso Correa   +3 more
doaj  

Treatment of a Large Cohort of Childhood Chronic Noninfectious Uveitis in a Multicentric Large Study: Adalimumab Versus Methotrexate as First‐Line Therapy

Arthritis &Rheumatology, EarlyView.
Objective Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in juvenile idiopathic arthritis–associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheumatology and ophthalmology units at Florence, Italy ...
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

Enfermedad de Kawasaki, reporte de casos Kawasaki disease: case report

Infectio, 2006
La enfermedad de Kawasaki es una vasculitis multisistémica, aguda, que ataca principalmente los niños lactantes y preescolares, y se ha convertido en la primera causa de enfermedad cardiaca adquirida en los países industrializados. Puede ser autolimitada,
JUAN CAMILO JARAMILLO, CARLOS ARTURO AGUIRRE   +1 more
doaj