Results 11 to 20 of about 76 (56)

Targeting alternative splicing as a novel approach to chemotherapy induced peripheral neuropathy [PDF]

open access: yes, 2021
Chemotherapy induced peripheral neuropathy (CIPN) is one of the most prevalent adverse effects of many chemotherapy drugs. It is estimated that up to 85% of patients suffer from CIPN during treatment and in many patients, painful neuropathy can continue ...
Swift, Matthew N.
core   +2 more sources

HIF1A is Overexpressed in Medulloblastoma and its Inhibition Reduces Proliferation and Increases EPAS1 and ATG16L1 Methylation

open access: yes, 2018
Background: Genetic and epigenetic modifications are closely related to tumor initiation and progression and can provide guidance for understanding tumor functioning, potentially leading to the discovery of new therapies.
Agda Karina Eterovic   +13 more
core   +1 more source

Evaluation of anti-neoplastic effects of NF-kB inhibition by DHMEQ (Dehidroximetilepoxiquinomicina) in medulloblastoma cell lines

open access: yes, 2014
Meduloblastoma é um câncer do sistema nervoso central, altamente invasivo, de origem embrionária, localizado no cerebelo. É mais comum em crianças e corresponde a aproximadamente 20% de todos os tumores intracranianos pediátricos.
Ramos, Priscila Maria Manzini
core   +1 more source

Arsenic trioxide as a possible radiosensitizer in pediatric medulloblastoma cell lines

open access: yes, 2018
O meduloblastoma (MB) é o tumor maligno cerebral mais frequente em crianças e adolescentes. Trata-se de uma doença heterogênea sob o aspecto genético, sendo reconhecido ao menos 12 subgrupos genético-moleculares, com impacto na apresentação ...
Paulo Henrique dos Santos Klinger
core   +2 more sources

Study of Modulation of the Wnt pathway by Aurora kinases inhibitor AMG900 in pediatric medulloblastoma cell lines

open access: yes, 2016
O meduloblastoma (MB) é o tumor cerebral maligno mais comum na infância. A formação/progressão desta neoplasia foi associada a alterações moleculares, que inclui a desregulação da via de sinalização Wingless (Wnt), responsável pelo desenvolvimento ...
Geron, Lenisa
core   +1 more source

Exploitation toward Nature in Hiaasen's Scat (2009): A Study of Ecocriticism [PDF]

open access: yes
Penelitian ini bertujuan untuk mengkaji efek dari deforestasi dan pengeboran minyak ilegal terhadap lingkungan. Penelitian ini menggunakan teori ekokritik untuk menganalisis efek dari eksploitasi. Data-data yang dibutuhkan dalam studi ini diambil dari
RAMADHAN, Muhammad Royhan
core  

Establishing a structure-activity-relationship for small molecule non-sugar glycomimetics [PDF]

open access: yes
DAOY Medullablastoma cells are highly invasive, mobile and can cause severe neurological and physical illness in patients affected by this cancer. Previous work by Wilkinson & Co-workers (2017) showed that some small-molecule non-sugar glycomimetic drugs
Dobiecki-Davies, J
core  

Evaluation of antineoplastic effects of Zebularine in medulloblastoma

open access: yes, 2016
O meduloblastoma (MB) é um câncer do sistema nervoso central, de origem embrionária, que surge no cerebelo. É o tumor maligno cerebral mais frequente na infância e corresponde a aproximadamente 20% de todos os tumores intracranianos pediátricos ...
Andrade, Augusto Faria
core   +1 more source

Exploring potential inhibitors of the HGF-Met signalling pathway as a prospective treatment for paediatric medulloblastoma [PDF]

open access: yes
Understanding the function of the HGF-Met signalling axis could present opportunities for new therapeutic treatments for cancer patients. The brain tumour Medulloblastoma is the leading cause of cancer-related death in children and infants meaning ...
Hoyles, NM
core  

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