Results 181 to 190 of about 298,099 (222)
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh +8 more
wiley +1 more source
Abstract Dinosaurs evolved a unique respiratory system with air sacs that contributed to their evolutionary success. Postcranial skeletal pneumaticity (PSP) has been used to infer the presence of air sac systems in some fossil archosaurs. While unambiguous evidence of PSP is well documented in pterosaurs and post‐Carnian saurischians, it remains absent
Tito Aureliano +3 more
wiley +1 more source
Abstract The anatomical description of the hourglass dolphin (Cephalorhynchus cruciger) and the spectacled porpoise (Phocoena dioptrica) remains largely unexplored, due to limited specimen availability and preservation challenges. This study employed digital imaging techniques, conventional histology, and computed tomography to provide visualization of
Jean‐Marie Graïc +26 more
wiley +1 more source
Trabecular bone ontogeny of the human talus
Abstract Studies of trabecular ontogeny may provide insight into the factors that drive healthy bone development. There is a growing understanding of how the juvenile skeleton responds to these influences; however, gaps in our knowledge remain. This study aims to identify ontogenetic trabecular patterns and regional changes during development within ...
Rebecca A. G. Reid +2 more
wiley +1 more source
ABSTRACT In patients with congenital cervical stenosis, the addition of abnormal cervical facet orientation (horizontal or hypoplastic joints) may predispose to segmental instability, subluxation, and canal compromise. Full assessment of facet anatomy is essential pre‐operatively, as selected patients (e.g., those with demonstrable subluxation, widened
Fawaz Almotairi +4 more
wiley +1 more source
ABSTRACT Pregnant patients with osteogenesis imperfecta type I are at increased risk of obstetric and hemorrhagic complications. Early multidisciplinary planning and anesthesiology involvement are essential. Severe postpartum hemorrhage may result from uterine atony and tissue fragility, requiring prompt uterotonic therapy, surgical intervention, blood
Madeline Dow +2 more
wiley +1 more source
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Bone density and fracture risk factors in ankylosing spondylitis: a meta-analysis
Osteoporosis International, 2023Fei Yan +3 more
semanticscholar +1 more source

