Results 131 to 140 of about 1,989,476 (247)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Bronquite infecciosa das galinhas: conhecimentos atuais, cepas e vacinas no Brasil Infectious bronchitis of chickens: current knowledge, strains and vaccines in Brazil

Ciência Rural, 2009
A bronquite infecciosa das galinhas (IB) é uma doença viral aguda e altamente contagiosa que provoca grandes perdas econômicas à indústria avícola em todo o mundo.
Juliana Figueiredo Pitangui Mendonça, Nelson Rodrigo da Silva Martins, Leandro Barbiéri de Carvalho, Marcos Eielson Pinheiro de Sá, Cristiano Barros de Melo   +4 more
doaj  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A nyugat-nílusi vírus virulencia markereinek vizsgálata [PDF]

, 2014
A WNV (WNV) egyes törzsei jelentős eltéréseket mutatnak neuroinvazivitás vonatkozásában. A WNV kettes genetikai vonalához tartozó teljes hosszúságú fertőző klón előállításával lehetőség nyílik különböző, a vírus patogenitását esetlegesen befolyásoló ...
Kuczmog, Zita
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Aspectos fisiológicos e fitossanitários na micropropagação para a obtenção de alho-semente livre de vírus [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Recursos Genéticos Vegetais, Florianópolis, 2012Com uso intensivo de mão-de-obra, tecnologia e capital, a cultura do alho no Brasil tem ...
Vieira, Renato Luís
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

TRANSMISSIBILIDADE DOMICILIAR - ABORDAGEM CLÍNICA DO VÍRUS INFLUENZA [PDF]

, 2018
O vírus influenza tem acometido mundialmente a população. A dispersão do vírus devido aos descuidos individual e coletivo são meios que favorecem a prevalência do vírus e sua resistência. No presente estudo, é discutida sobre a transmissibilidade no meio
Bernardo, Alana Beatriz Silva, Teixeira, Claudio Silva, Chaves, Karen Cristina Barbosa, Júnior, Geraldo Eustáquio da Costa, Duarte, Angélica Souza, da Silveira, Fernanda Rodrigues   +5 more
core