Results 181 to 190 of about 64,869 (199)

Late Kidney Graft Dysfunction Related to JC Virus Nephropathy

Kidney Medicine
Sarah Bensaou, Antoine Morel, Marie Matignon, Thomas Stehle, Anissa Moktefi   +4 more
doaj   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

The Immunosuppression Paradox in Multiple Sclerosis: Are We Fueling the Fire by Suppressing Immunity in an Epstein-Barr Virus-Linked Disease? [PDF]

Open Forum Infect Dis
Onisiforou A.
europepmc   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Causal effects of antibody-mediated immunity to pathogens on five ophthalmic diseases: a Mendelian randomization study. [PDF]

Exp Biol Med (Maywood)
Pan L, Deng J, Yang J, Wang M, Chen Z, Wang T, Li Y.   +6 more
europepmc   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source

JC Virus Agnogene Regulates Histone-Modifying Enzymes via PML-NBs: Transcriptomics in VLP-Expressing Cells. [PDF]

Viruses
Shishido-Hara Y, Yaoi T.
europepmc   +1 more source

Pathogenic dengue virus TW2015 strain infection triggers anaerobic glycolysis and enhances mortality in diabetic mice. [PDF]

J Virol
Kuo Y-P, Dai S-S, Lin E-J, Jane W-N, Tsai W-H, Tsai W-T, Imana ZN, Tung W-J, Su Y-S, Tien C-F, Yu C-Y, Chen C-H, Yu G-Y.   +12 more
europepmc   +1 more source

CRISPR-based assays for the detection of BK virus and JC virus infections post-kidney transplantation. [PDF]

Mil Med Res
Liu Y, Xu JS, Cao L, Yang S, Li TM, Huang HQ, Zhang JH, Zhao X, Liu Q, Li S, Li M, Wang H.   +11 more
europepmc   +1 more source