Results 41 to 50 of about 6,435 (185)

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Sử DụNG ỐC BƯƠU VàNG LàM THứC ĂN Bổ SUNG PROTEIN TRONG KHẩU PHầN VịT THịT [PDF]

open access: yes, 2010
Một nghiên cứu trên vịt được thực hiện tại tỉnh Đồng Tháp để đánh giá sử dụng ốc bươu vàng làm thức ăn bổ sung protein thay thế bánh dầu đậu nành trong khẩu phần nuôi vịt thịt từ 28 đến 60 ngày tuổi.
Bùi Xuân Mến, Nguyễn Thành Công
core  

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

open access: yesAdvanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng   +20 more
wiley   +1 more source

Vitamin B6 Supplementation Improves Oxidative Stress and Enhances Serum Paraoxonase/Arylesterase Activities in Streptozotocin-Induced Diabetic Rats

open access: yesThe Scientific World Journal, 2014
The purpose of this study was to investigate the effects of vitamin B6 (Vit B6) on oxidant and antioxidant status in streptozotocin-induced diabetic rats.
Sibel Taş   +2 more
doaj   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

open access: yesAdvanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li   +23 more
wiley   +1 more source

BệNH TíCH ĐạI THể Ở VịT ĐƯợC Mổ KHáM TạI Lò Mổ GIA CầM THàNH PHố CAO LãNH - TỉNH ĐồNG THáP

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2014
Khảo sát bệnh tích đại thể trên vịt được giết mổ tại lò mổ gia cầm Thành phố Cao Lãnh nhằm xác định tỷ lệ bệnh tích và các dạng bệnh tích thường xuất hiện trên vịt sau khi giết mổ.
Nguyễn Phúc Khánh   +2 more
doaj  

When Biology Meets Medicine: A Perspective on Foundation Models

open access: yesAdvanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu   +3 more
wiley   +1 more source

Benefits of venom immunotherapy: How soon can they be expected [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2017
Introduction/Objective. Allergic reactions to insect stings are medical emergencies that could be prevented by venom immunotherapy (VIT). The main purpose of VIT is to prevent fatal or life-threatening reactions.
Kadivec Saša, Košnik Mitja
doaj   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Current Standards of Monitoring Models in Healthcare Settings

open access: yesAdvanced Intelligent Discovery, EarlyView.
AI/ML‐enabled medical devices are entering clinical practice faster than monitoring standards mature. This review highlights gaps in postmarket surveillance, limited use of predetermined change‐control plans, and the need for ongoing performance tracking, drift detection, explainability, and workflow‐aware governance to support safer, more reliable ...
Alan Kay   +5 more
wiley   +1 more source

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