Results 111 to 120 of about 9,362,172 (272)

The South American fruit fly : an important pest insect with RNAi-sensitive larval stages [PDF]

, 2019
RNA interference (RNAi) technology has been used in the development of approaches for pest control. The presence of some essential genes, the so-called "core genes," in the RNAi machinery is crucial for its efficiency and robust response in gene ...
Cagliari, Deise, Dias, Nayma, Kremer, Frederico Schmitt, Nava, Dori Edson, Rickes, Leticia Neutzling, Smagghe, Guy, Zotti, Moises   +6 more
core   +1 more source

The V-ATPase regulates localization of the TRP Ca2+ channel Yvc1 in response to oxidative stress in Candida albicans

International Journal of Medical Microbiology, 2020
The vacuolar-type H+-ATPase (V-ATPase) is a highly conserved protein complex among the eukaryotic cells. We previously revealed that both the V-ATPase and the transient receptor potential (TRP) channel Yvc1 are involved in oxidative stress response (OSR).
Liping Peng, Qilin Yu, Hangqi Zhu, Nali Zhu, Bing Zhang, Henan Wei, Jiachun Xu, Mingchun Li   +7 more
doaj   +1 more source

Regulatory assembly of the vacuolar proton pump VOV1-ATPase in yeast cells by FLIM-FRET

, 2010
We investigate the reversible disassembly of VOV1-ATPase in life yeast cells by time resolved confocal FRET imaging. VOV1-ATPase in the vacuolar membrane pumps protons from the cytosol into the vacuole. VOV1-ATPase is a rotary biological nanomotor driven
Batisse, Claire, Boersch, Michael, Boettcher, Bettina, Ernst, Stefan, Zarrabi, Nawid   +4 more
core   +1 more source

HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification [PDF]

, 2017
Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are ...
Asensio, Cedric S, Burns, Christian, Chen, Lan, de Leeuw, Noah F, Fitzpatrick, James A. J., Hosford, Bethany, Hummer, Blake H, Joens, Matthew S   +7 more
core   +2 more sources

The acid test of v-ATPase function [PDF]

Journal of Cell Biology, 2010
The vesicular protein complex has a dual role in sorting and degrading neuronal proteins.
openaire   +2 more sources

Regulation and function of V-ATPases in physiology and disease

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2020
The vacuolar H+-ATPases (V-ATPases) are essential, ATP-dependent proton pumps present in a variety of eukaryotic cellular membranes. Intracellularly, V-ATPase-dependent acidification functions in such processes as membrane traffic, protein degradation, autophagy and the coupled transport of small molecules.
Michael Forgac, Michael Collins
openaire   +3 more sources

The Emerging Roles of Vacuolar-Type ATPase-Dependent Lysosomal Acidification in Cardiovascular Disease

Biomolecules
The vacuolar-type ATPase (V-ATPase) is a multi-subunit enzyme complex that maintains lysosomal acidification, a critical process for cellular homeostasis.
Yan-Yan Chen, Cai-Xia Liu, Hai-Xin Liu, Shi-Yuan Wen   +3 more
doaj   +1 more source

Interaction of the late endo-lysosomal lipid PI(3,5)P2 with the Vph1 isoform of yeast V-ATPase increases its activity and cellular stress tolerance

Journal of Biological Chemistry, 2019
The low-level endo-lysosomal signaling lipid, phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2), is required for full assembly and activity of vacuolar H+-ATPases (V-ATPases) containing the vacuolar a-subunit isoform Vph1 in yeast.
Subhrajit Banerjee, Kaitlyn Clapp, Maureen Tarsio, P. Kane   +3 more
semanticscholar   +1 more source

In situ analysis of pH gradients in mosquito larvae using non-invasive, self-referencing, pH-sensitive microelectrodes

, 2001
The alkaline environment, pH approximately 11, in the anterior midgut lumen of mosquito larvae is essential for normal nutrition and development. The mechanism of alkalization is, however, unknown.
Boudko, D.Y., Harvey, W.R., Linser, P.J., Moroz, L.L., Smith, P.J., Trimarchi, J.R.   +5 more
core  

Fehérjék membránba ágyazódásának, szerveződésének és lipidekkel való kölcsönhatásának biofizikája = Biophysics of protein insertion and folding in membranes and their interaction with lipids [PDF]

, 2007
1. A vakuólum ATPáz (V-ATPáz). Ez a membránkötött molekuláris motor az ATP hidrolízisből nyert kémiai energia révén protonokat pumpál a membránon keresztül, ami miatt a csontritkulás potenciális terápiájában ez az egyik kulcs target enzim.
Bérczi, Alajos, Debreceny, Mónika, Kónya, Erika, Kóta, Zoltán, Páli, Tibor László, Szalontai, Balázs   +5 more
core