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V-ATPase, ScNhx1p and Yeast Vacuole Fusion
Journal of Genetics and Genomics, 2012Membrane fusion is the last step in trafficking pathways during which membrane vesicles fuse with target organelles to deliver cargos. It is a central cellular reaction that plays important roles in signal transduction, protein sorting and subcellular compartmentation.
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Rotation, Structure, and Classification of Prokaryotic V-ATPase
Journal of Bioenergetics and Biomembranes, 2005The prokaryotic V-type ATPase/synthases (prokaryotic V-ATPases) have simpler subunit compositions than eukaryotic V-ATPases, and thus are useful subjects for studying chemical, physical and structural properties of V-ATPase. In this review, we focus on the results of recent studies on the structure/function relationships in the V-ATPase from the ...
Ken, Yokoyama, Hiromi, Imamura
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The V-ATPase inhibitor archazolid
2014Fighting metastasis is a major challenge in cancer therapy and novel therapeutic targets and drugs are highly appreciated. Resistance of invasive cells to anoikis, a particular type of apoptosis induced by loss of cell-extracellular matrix (ECM) contact, is a major prerequisite for their metastatic spread. Inducing anoikis in metastatic cancer cells is
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V-ATPase inhibitor targets Ras-mutant cancers
Nature Reviews Drug Discovery, 2022openaire +2 more sources
A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps
Nature Reviews Molecular Cell Biology, 2010Bjørn P. Pedersen +2 more
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A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy
Cell, 2019Yue Xu, Ping Zhou, Qiuhe Lu
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