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Proton-pump inhibitors and risk of renal disease [PDF]
Journal of Nephropharmacology, 2017 Proton pump inhibitors (PPIs) are one group of drugs that inhibit gastric acid secretion by binding irreversibly to the gastric proton pump to the gastric proton pump.
Mahrang Hedaiaty +3 more
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South African Family Practice, 2015 Proton-pump inhibitors (PPIs) are a class of drugs that profoundly suppress gastric acid secretion, and thus have become the treatment of choice for gastro-oesophageal reflux disease and peptic ulcer disease. PPIs are considered safe and effective. It is
Vasudevan G. Naidoo
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Deprescribing proton pump inhibitors
Singapore Medical Journal, 2023 Kim Jun Kevin Teh +3 more
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FEBS Letters, 2007 Chemiosmotic circuits of plant cells are driven by proton (H+) gradients that mediate secondary active transport of compounds across plasma and endosomal membranes. Furthermore, regulation of endosomal acidification is critical for endocytic and secretory pathways.
Gaxiola, Roberto A. +2 more
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Multimorbidities and Overprescription of Proton Pump Inhibitors in Older Patients. [PDF]
PLoS ONE, 2015 To determine whether there is an association between overprescription of proton pump inhibitors (PPIs) and multimorbidities in older patients.Multicenter prospective study.Acute geriatric medicine at the University Hospital of Nantes and the Hospital of ...
Anne Delcher +5 more
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Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients. [PDF]
PLoS ONE, 2018 BACKGROUND:Proton pump inhibitor use is associated with incident chronic kidney disease, chronic kidney disease progression and end-stage renal disease.
Hee Jeong Lee +8 more
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Use of Proton Pump Inhibitors in Hungary: Mixed-Method Study to Reveal Scale and Characteristics
Frontiers in Pharmacology, 2020 BackgroundDue to their efficacy and tolerability, utilization of proton pump inhibitors (PPI) has significantly increased worldwide. Parallel to the clinical benefits, potential long-term side effects have been observed, which, along with increasing ...
Mária Matuz +7 more
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Clinical and Experimental Dental Research, 2022 Objectives Proton pump inhibitors, such as omeprazole and pantoprazole, are frequently prescribed for the treatment of acid reflux. However, those medications have been shown to affect a variety of physiologic processes, including bone homeostasis and ...
Bhavneet K. Chawla +3 more
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Critical Care Explorations, 2021 OBJECTIVES:. Histamine-2 receptor antagonists are commonly administered for stress ulcer prophylaxis in critically ill adults and may be associated with delirium development.
Ami Shiddapur, BS +3 more
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Biomedicines, 2022 (1) Background: Hepatic encephalopathy (HE) is a common complication in cirrhosis patients, and recently, clinical evidence indicates that a higher risk of HE is associated with the usage of proton pump inhibitors.
Pan Zhang +6 more
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