Results 11 to 20 of about 108,823 (265)
Deprescribing proton pump inhibitors
Singapore Medical Journal, 2023 Kim Jun Kevin Teh +3 more
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FEBS Letters, 2007 Chemiosmotic circuits of plant cells are driven by proton (H+) gradients that mediate secondary active transport of compounds across plasma and endosomal membranes. Furthermore, regulation of endosomal acidification is critical for endocytic and secretory pathways.
Gaxiola, Roberto A. +2 more
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Proton Diet for the Sodium Pump, [PDF]
Biochemistry, 2010 In the absence of Na(+) and K(+) ions the Na,K-ATPase shows a pH-dependent ATP hydrolysis that can be inhibited by ouabain. At pH 7.2 this activity is 5% of the maximal under physiological conditions. It could be inferred that this activity is associated with H(+) transport in both directions across the membrane and facilitates an H-only mode of the ...
Apell, Hans-Jürgen +2 more
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Journal of Medical Case Reports, 2021 Background Proton pump inhibitors are frequently used (and often overused) medications with adverse effects including vitamin B12 deficiency, Clostridium difficile colitis, and increased risk of chronic kidney disease.
Theodore W. Perry
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Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors
Gastroenterology Research and Practice, 2015 In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature.
Simone Janett +7 more
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ENDOSCOPIC AND HISTOPATHOLOGIC GASTRIC CHANGES IN CHRONIC USERS OF PROTON-PUMP INHIBITORS
Arquivos de Gastroenterologia, 2015 Background Proton-pump inhibitors have been used for at least two decades. They are among the most commonly sold drugs in the world. However, some controversy remains about the indications for their use and the consequences of their prolonged use ...
Sílvia Maria Perrone CAMILO +5 more
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Proton Pumps: Molecular Mechanisms, Inhibitors and Activators of Proton Pumping
International Journal of Molecular Sciences, 2023 Protein molecular machines, also known as proton pumps, are the most important element of biological membranes [...]
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Iron deficiency anemia from iron malabsorption caused by proton pump inhibitors
eJHaem, 2020 Background Iron deficiency anemia without evidence for blood loss can present a diagnostic challenge. Proton pump inhibitors have been associated with iron deficiency anemia for many years, yet the relationship between the two until recently was not ...
Michael Boxer
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Omeprazole-induced and pantoprazole-induced asymptomatic hyponatremia: a case report
Journal of Medical Case Reports, 2020 Background Hyponatremia is the most common electrolyte disorder. Thiazides, antidepressants, antipsychotic drugs, and antiepileptic drugs are well-known causes of hyponatremia. Proton pump inhibitor use is a rare cause of hyponatremia and, when reported,
Isabel J. B. van der Zalm +2 more
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Modified Rhodopsins From Aureobasidium pullulans Excel With Very High Proton-Transport Rates
Frontiers in Molecular Biosciences, 2021 Aureobasidium pullulans is a black fungus that can adapt to various stressful conditions like hypersaline, acidic, and alkaline environments. The genome of A. pullulans exhibits three genes coding for putative opsins ApOps1, ApOps2, and ApOps3.
Sabine Panzer +9 more
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