Proton pump inhibitors overuse - consequences among patients
Journal of Education, Health and Sport, 2019 Introduction Omeprazole was first proton pump inhibitor (PPI) approved for use by patients. Thirty years have passed since then. Due to their effectiveness, low price and safety proton pump inhibitors have become one of the most frequently prescribed ...
Patrycja Kmiotek +2 more
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Overprescribing proton pump inhibitors [PDF]
BMJ, 2008 Proton pump inhibitors are one of the most frequently prescribed classes of drug in the world because they combine a high level of efficacy with low toxicity. In 2006, expenditure on these drugs was £425m (€595m; $872m) in England1 and £7bn globally.2 Yet studies consistently show that proton pump inhibitors are being overprescribed worldwide in both ...
Ian, Forgacs, Aathavan, Loganayagam
openaire +2 more sources
Structures and proton-pumping strategies of mitochondrial respiratory enzymes [PDF]
, 2001 Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the energy made available from electron transfer reactions to transport protons across the inner mitochondrial membrane and create an electrochemical gradient used for the ...
Chan, Sunney I., Schultz, Brian E.
core +1 more source
Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: A meta-analysis [PDF]
, 2005 Aim: To systematically evaluate the efficacy of H2-receptor antagonists (H2RAs) and proton pump inhibitors in healing erosive esophagitis (EE). Methods: A meta-analysis was performed.
Huang, JQ +6 more
core +1 more source
Risk of Bacterial Infection from Proton Pump Inhibitor Use
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017 Currently, proton pump inhibitors are used in a wide range of patients with gastroesophageal reflux disease, peptic ulcer, and upper gastrointestinal symptoms such as dyspepsia.
Sung Soo Kim +7 more
doaj +1 more source
Regular proton pump inhibitor use and incident dementia: population-based cohort study
BMC Medicine, 2022 Background To examine the association between regular use of proton pump inhibitors and the risk of incident dementia, including dementia subtypes, and whether the association differs between APOE genotypes.
Peidong Zhang +9 more
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Proton pump inhibitors are associated with increased risk of development of chronic kidney disease [PDF]
, 2016 Background Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD).
Arora, Pradeep +6 more
core +2 more sources
Correlated photon-pair generation in a periodically poled MgO doped stoichiometric lithium tantalate reverse proton exchanged waveguide [PDF]
, 2011 We demonstrate photon-pair generation in a reverse proton exchanged waveguide fabricated on a periodically poled magnesium doped stoichiometric lithium tantalate substrate.
Bonneau, D. +15 more
core +2 more sources
Journal of Medical Case Reports, 2021 Background Proton pump inhibitors are frequently used (and often overused) medications with adverse effects including vitamin B12 deficiency, Clostridium difficile colitis, and increased risk of chronic kidney disease.
Theodore W. Perry
doaj +1 more source
Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors
Gastroenterology Research and Practice, 2015 In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature.
Simone Janett +7 more
doaj +1 more source