Results 61 to 70 of about 443,126 (283)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Tomato Yellow Leaf Curl Virus V2 Protein Plays a Critical Role in the Nuclear Export of V1 Protein and Viral Systemic Infection

open access: yesFrontiers in Microbiology, 2020
Geminiviruses are an important group of circular, single-stranded DNA viruses that cause devastating diseases in crops. Geminiviruses replicate their genomic DNA in the nucleus and the newly synthesized viral DNA is subsequently transported to the ...
Wenhao Zhao   +7 more
doaj   +1 more source

A theory of a saliency map in primary visual cortex (V1) tested by psychophysics of color-orientation interference in texture segmentation [PDF]

open access: yes, 2006
It has been proposed that V1 creates a bottom-up saliency map, where saliency of any location increases with the firing rate of the most active V1 output cell responding to it, regardless the feature selectivity of the cell.
Jingling, L., Zhaoping, L.
core  

Functional Organization of Visual Cortex in the Owl Monkey [PDF]

open access: yes, 2004
In this study, we compared the organization of orientation preference in visual areas V1, V2, and V3. Within these visual areas, we also quantified the relationship between orientation preference and cytochrome oxidase (CO) staining patterns. V1 maps of
Shima, D.   +5 more
core   +1 more source

flyingtext/yulryeo: Yulryeo: Prime number repository v1 (20230328)

open access: yes, 2023
율려: 소수 저장소 v1 (20230328) Yulryeo: Prime number repository v1 (20230328) Detailed information is in ...
Jihyeon Yoon
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Rare Earth Elements in the Energy Transition: A Review of the Demand-Sustainability-Risk Nexus and Future Perspectives

open access: yesEng
The global transition toward renewable energy and decarbonization is intrinsically linked to the management of critical materials. Rare Earth Elements (REEs) are no exception, as they play a strategic role at the center of climate goals.
Victor Osvaldo Vega-Muratalla   +4 more
doaj   +1 more source

Adaptive gain modulation in V1 explains contextual modifications during bisection learning. [PDF]

open access: yesPLoS Computational Biology, 2009
The neuronal processing of visual stimuli in primary visual cortex (V1) can be modified by perceptual training. Training in bisection discrimination, for instance, changes the contextual interactions in V1 elicited by parallel lines. Before training, two
Roland Schäfer   +2 more
doaj   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Prediction of Left Main Coronary Artery Obstruction by 12‐Lead Electrocardiography: ST Segment Deviation in Lead V6 Greater than or Equal to ST Segment Deviation in Lead V1

open access: yesAnnals of Noninvasive Electrocardiology, 2006
Background: Acute coronary syndrome (ACS) resulting from culprit lesion in left main coronary artery (LMCA) can cause rapid hemodynamic deterioration. It is important to identify these patients early to facilitate timely revascularization.
Nitin Mahajan   +8 more
doaj   +1 more source

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