Results 131 to 140 of about 13,554,997 (301)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Slip-on dress, 1917

open access: yes, 1917
Pattern No. 3721: Dress with double collar, and sleeves that are "gathered to straight cuffs rolled back at the wrists and faced." Both the collars and cuff facings are of a contrasting material. Neckline is fastened with two button closures. Wide girdle
Vogue Pattern Service
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Dance frock, 1919

open access: yes, 1919
Pattern No. 4788: Shirtwaist with a round neckline, girdle that ties in the back, and "transparent modesty gathered by a ribbon." Neckline and short sleeves trimmed with metal bead fringe.
Vogue Pattern Service
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Misses' cape with set-in pockets and deep buttoned collar, 1920

open access: yes, 1920
Pattern No. 4784: Cape with a deep collar and set-in pockets that are a "continuation of the side slashes for the hands." "Cape opens at the center front and fastens at the yoke line with two buttons and a cord." Pockets and collar are finished with ...
Vogue Pattern Service
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The effect of changes in nutritional components and environmental factors on growth pattern and biofilm formation by Mycobacterium marinum CCUG 20998

open access: yesBiological Journal of Microorganism, 2015
 Introduction: Mycobacterium marinum is a slow growing nontuberculosis mycobacterium. This organism can cause disseminated granulomatous infections in fish, called ‘fish tuberculosis’.
Azam Sheidadost   +2 more
doaj  

Belted coat with kimona-style sleeves, 1919

open access: yes, 1919
Pattern No. 4698: Wide-collared coat with waistcoat panels. Side sections and flared-cuff sleeves are cut kimona-style and "seamed to the front and back panels under a lapped plait." Front of the coat is slashed at either side to accommodate the narrow ...
Vogue Pattern Service
core  

Inferior Oblique Muscle Surgery for Treatment of V-pattern Strabismus and Dissociated Vertical Deviation

open access: yes
The inferior oblique muscle plays a key role in controlling eye position during changes in gaze direction, particularly in coordinating vertical and torsional movements.
Agata J. Ordon, Piotr Loba
core   +1 more source

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