Results 141 to 150 of about 13,554,997 (301)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 1920 Pattern No. 4306: Collared surplice shirtwaist with a narrow girdle that is drawn through slashes at either side and fastens at the left side with a button; girdle is trimmed with embroidery. Sleeves are "darted from the lower edge to fit the arm snugly,
Vogue Pattern Service
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 1919 Pattern No. 4781: Collared wrap that is slashed at either side for a straight belt that buckles at the front; the slashes are finished with "a narrow applied fold and cornered with embroidered arrows." "Slashes are extended for the inserted pockets which
Vogue Pattern Service
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Flounced frock with ribbon and lace trim, 1919
, 1919 Pattern No. 4654: Sleeves are "slashed and trimmed with wide bands of lace and ribbon." Collar is gathered and trimmed with a tiny ribbon bow. Shirtwaist and skirt panel are trimmed with wide bands of lace and tiny ribbon bows.
Vogue Pattern Service
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Horizontal muscle transposition or oblique muscle weakening for the correction of V pattern? [PDF]
Eye (Lond), 2014 Sekeroglu HT +4 more
europepmc +1 more source