Results 221 to 230 of about 13,554,997 (301)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Integrated Cranio-Cervical Organization in Adults: Association Between Morphocranial Pattern and Segmental Cervical Alignment After Orthodontic Treatment. [PDF]

J Clin Med
Serra Alierta M, Sánchez-Molins M, Casado Rodriguez A, Manzanares Cespedes MC, Olivieri JG.   +4 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A Case of a 40-year-old Female with Speech Disturbance. [PDF]

Ann Clin Transl Neurol
Lorah V, Robers MV.
europepmc   +1 more source

Central Auditory Pathway Dysfunction in Type 2 Diabetes Mellitus: A Narrative Review of Auditory Brainstem Response Alterations. [PDF]

Cureus
Abbass A, Waheed S, Kaur V, Bobbara A, Anand A.   +4 more
europepmc   +1 more source

Combining in vitro and in silico approaches to model neural tube patterning and isthmic organizer formation. [PDF]

NPJ Syst Biol Appl
Bertilsson F, Degener A, Ibek P, Rathore GS, Andersson E, Rifes P, Kirkeby A, Olariu V.   +7 more
europepmc   +1 more source

Spotted Patterns of Glass Frogs Can Disguise Imperfections in Transparency to Improve Camouflage. [PDF]

Ecol Evol
Yeager J, Ávila L, Barnett JB.
europepmc   +1 more source