Results 121 to 130 of about 67,456 (239)

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

WTAP‐mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy

Journal of Diabetes Investigation, EarlyView.
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Yutong Li, Wenhua Chen, Jianhao Lu, Xiaoyue Lin, Ying Tang, Jiaxu Li, Mingwei Chen   +6 more
wiley   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

Effect of substructure fabrication method and design on the fracture resistance properties of metal–ceramic restorations

Journal of Prosthodontics, EarlyView.
Abstract Purpose In metal–ceramic restorations, the substructure fabrication method and design may affect the prognosis of the prosthesis. This study evaluated and compared the fracture resistance of metal–ceramic restorations fabricated with different substructure fabrication methods using two different alloy powders and designs.
Young‐Hoon Lee, Yoon‐Hyuk Huh, Chan‐Jin Park, Lee‐Ra Cho, Kyung‐Ho Ko   +4 more
wiley   +1 more source

VAC machine in Science Lab, ca. 1985

, 1985
b&w photographVery good condition.Two students operate the VAC machine in ...

core   +1 more source

Examining determinants of COVID-19 vaccine hesitancy and acceptance among Arab university students: A regional scoping review. [PDF]

Hum Vaccin Immunother
Gambescia SF, Tran V, Almoayad F, Aboul-Enein BH.   +3 more
europepmc   +1 more source

Effect of metal framework design on the fracture resistance of implant‐supported metal–ceramic crowns fabricated by selective laser melting

Journal of Prosthodontics, EarlyView.
Abstract Purpose To evaluate the fracture resistance of implant‐supported metal–ceramic crowns fabricated using selective laser melting (SLM), according to the metal support height around the screw access hole (SAH) and the substructure design. Materials and Methods Metal–ceramic crowns and rectangular bilayer specimens were fabricated using SLM in two
Sang‐Ah Lee, Kyung‐Ho Ko, Yoon‐Hyuk Huh, Chan‐Jin Park, Lee‐Ra Cho   +4 more
wiley   +1 more source

The role of negative-pressure wound therapy in Fournier's gangrene: Association with mortality. [PDF]

Ulus Travma Acil Cerrahi Derg
Dogan AE, Sanci A, Aydın MY, Ekenci BY, Hepsen E, Ozenc G, Altan M, Karakoyunlu AN.   +7 more
europepmc   +1 more source

A dose‐escalated radiation protocol of 10 × 4.0 Gy provides long‐term local control in canine apocrine gland anal sac adenocarcinoma

Journal of Small Animal Practice, EarlyView.
Objectives To obtain insights for establishing radiation therapy strategies that provide long‐term locoregional benefits in canine apocrine gland anal sac adenocarcinoma, we evaluated whether a dose‐escalated protocol (10 × 4.0 Gy) could improve clinical outcomes, particularly long‐term locoregional control, while maintaining acceptable toxicity ...
M. Terauchi, Y. Fujii, R. Iwasaki, T. Mori   +3 more
wiley   +1 more source

The impact of TcdB conformational dynamics on vaccination against Clostridioides difficile. [PDF]

PLoS Pathog
Kempher ML, Shadid TM, Lang GA, Honold ST, May JN, Hall EJ, Larabee JL, Lang ML, Ballard JD.   +8 more
europepmc   +1 more source