Results 221 to 230 of about 5,753 (291)

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

A Novel Application of Virus Like Particles in the Hemagglutination Inhibition Assay. [PDF]

Int J Mol Sci
El-Husseiny MH, Pushko P, Tretyakova I, Hagag NM, Abdel-Mawgod S, Shabaan A, Bakry NR, Arafa AS.   +7 more
europepmc   +1 more source

Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles

Small, EarlyView.
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber, Na Liu, Laurianne Simon, Franziska Adermann, Vivien Bachmann, Lucas Gath, Stephanie Hoeppener, Stephanie Schubert, Oliver Werz, Vincent Lapinte, Marie Morille, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +14 more
wiley   +1 more source

Lymphoma patients treated with anti-CD20 and chemotherapy display disconnected T and B cell responses to COVID-19 vaccine. [PDF]

Front Immunol
Lamure S, Chavez HH, de Goër de Herve MG, Fornecker LM, Drenou B, Jacquet C, Merabet F, Kohn M, Quélin F, Jackson A, Choquet S, Duléry R, Taoufik Y, Besson C.   +13 more
europepmc   +1 more source

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

Small, EarlyView.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk, Rima Nuwayhid, Stefaniya Gaydarova, Eva Bittrich, Natalia Makarova, Susanne Boye, Christo Tzachev, Jan C. Simon, Sandra Franz, Albena Lederer   +9 more
wiley   +1 more source

[Vaccination coverage against COVID-19 in healthcare workers and associated factors in the city of Yaoundé in July 2022]. [PDF]

Pan Afr Med J
Koïngakiawa SOB, Nzougouat JL, Edzoa BE, Tonga C.   +3 more
europepmc   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

Small, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi, Tijana Maric, Isidro Badillo‐Ramírez, Juliane Fjelrad Christfort, Matteo Tollemeto, Carmen Milan Guimera, Casper Nisula, Giulia Zappalá, Laura De Vittorio, Marta Rubio‐Huertas, Sungyeong Kim, Ziqiao Li, Morten Bo Søndergaard Svendsen, Zhongyang Zhang, Anja Boisen   +14 more
wiley   +1 more source

Modeling the Effects of Vaccination and Treatment With Third-Generation Macrolides or Oxytetracyclines on Persistence and Impact of Contagious Bovine Pleuropneumonia. [PDF]

Transbound Emerg Dis
Mariner JC, Wesonga H, Muuka G, Stuke K, Colston A, Wilson S.   +5 more
europepmc   +1 more source

Assessment of sampling variation applets during development

Teaching Statistics, EarlyView.
Abstract Concepts relating to sampling variation are known to be difficult for learners in introductory classes. There is some evidence that web‐based visualization tools, or “applets,” may aid the learning of these challenging ideas. Four freely available applets developed at the authors' institution were extensively tested through sessions involving ...
Bruce Dunham, Nancy Heckman, Melissa Lee, Mike Whitlock, Gaitri Yapa   +4 more
wiley   +1 more source

Assessing the Efficacy and Immunogenicity of Anticaries Vaccine-A Systematic Review and Meta-Analysis. [PDF]

Immun Inflamm Dis
Kumar G, Dash P, Nanda SB, Fareed M, Karobari MI.   +4 more
europepmc   +1 more source