Results 51 to 60 of about 3,236 (244)

Analysis of Whole-Genome Sequences of Infectious laryngotracheitis Virus Isolates from Poultry Flocks in Canada: Evidence of Recombination

Viruses, 2020
Infectious laryngotracheitis virus (ILTV) is a herpes virus that causes an acute respiratory disease of poultry known as infectious laryngotracheitis (ILT).
Ana Perez Contreras, Frank van der Meer, Sylvia Checkley, Tomy Joseph, Robin King, Madhu Ravi, Delores Peters, Kevin Fonseca, Carl A. Gagnon, Chantale Provost, Davor Ojkic, Mohamed Faizal Abdul-Careem   +11 more
doaj   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

STUDY OF SAFETY OF PAROTITIS VACCINE

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Monitoring of post-vaccinal complications in children immunized with a parotitis vaccine. Materials and methods. Observation of198 945 children, immunized with 16 lots of parotitis vaccine with Leningrad-3 strain (L-3), was carried out for 3 years ...
G. M Ignatiev, M. V Kulak, E. V Otrashevskaya, E. K Bukin, A. E Nesterov, M. A Gorbunov, V. N Mikheev   +6 more
doaj  

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

OUTER MEMBRANE PROTEIN PROFILING OF PASTEURELLA MULTOCIDA [PDF]

Pakistan Veterinary Journal, 2007
Outer membrane proteins (OMPs) play a significant role in the pathogenesis of Pasteurellosis. OMPs of Pasteurella multocida (P. multocida) B:2 strain were characterized by using sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE ...
R. MUNIR, D. SHAHWAR1, U. FAROOQ, I. NAWAZ1, I. SHAHZAD1 AND A. KHANUM1
doaj  

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

STUDY OF NEUROVIRULENT PROPERTIES OF VACCINE AGAINST CULTURAL LIVE RUBELLA

Педиатрическая фармакология, 2010
Experts at FSUE R&D Centre Microgen of the RF’s Healthcare Ministry have developed a national drug designed to prevent rubella — Cultural live vaccine against rubella on the basis of vaccinal strain RA 27/3.
A.N. Mironov, A.A. Tsaan, D.S. Bushmenkov, A.A. Romanova, V.A. Merkulov, N.N. Stepanov   +5 more
doaj   +2 more sources

A Study of Biokinetic Peculiarities and Optimization of the Conditions for Culturing Vibrio cholerae Strains Overproducing Protective Antigens Suitable for Use in the Production

Проблемы особо опасных инфекций, 2008
Described in the work are the major biokinetic criteria of the submerged growth process of V. cholerae Ol strains (classical and eltor biovars), O139, non-Ol and non-O139 serogroups, capable of overproducing the main protective antigens (Ol and O139 ...
O. A. Volokh, I. A. Shepelev, S. P. Zadnova, I. M. Krepostnova, S. A. Yeremin   +4 more
doaj   +1 more source

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source