Results 151 to 160 of about 622,873 (307)

The Case for Vaccination [PDF]

, 1903
C.‐E. A. Winslow
openalex   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

DNA methylation as a triage tool for cervical cancer screening – A meeting report

Preventive Medicine Reports
Introduction: DNA methylation is proposed as a novel biomarker able to monitor molecular events in human papillomavirus (HPV) infection pathophysiology, enabling the distinction between HPV-induced lesions with regression potential from those that may ...
F. Ricardo Burdier, Dur-e-Nayab Waheed, Belinda Nedjai, Renske D.M. Steenbergen, Mario Poljak, Marc Baay, Alex Vorsters, Severien Van Keer   +7 more
doaj  

Impact of the COVID-19 pandemic on the timeliness of pertussis-containing vaccination: A cohort study in Shanghai, China. [PDF]

Hum Vaccin Immunother
Huang Z, Wu Y, Gao M, Wang N, Ma Z, Zhang S, Yang M, Wang X, Zhao D, Wen Z, Zhou W, Zheng B, Tian J, Wang W.   +13 more
europepmc   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

Toward ‘Vaccine Internationalism’: The Need for an Equitable and Coordinated Global Vaccination Approach to Effectively Combat COVID-19

International Journal of Public Health, 2021
Brian L. H. Wong, Brian L. H. Wong, Manfred S. Green, Manfred S. Green, John Reid, John Reid, Jose M. Martin-Moreno, Jose M. Martin-Moreno, Jose M. Martin-Moreno, Nadav Davidovitch, Nadav Davidovitch, Laurent Chambaud, Laurent Chambaud, Lore Leighton, Mohamud Sheek-Hussein, Mohamud Sheek-Hussein, Ranjeet Dhonkal, Ranjeet Dhonkal, Robert Otok, John D. Middleton, John D. Middleton   +20 more
doaj   +1 more source

RSV vaccination uptake among adults aged 60 years and older in the United States during the 2023-2025 vaccination seasons. [PDF]

Hum Vaccin Immunother
La EM, McGuiness CB, Singer D, Yasuda M, Chen CC.   +4 more
europepmc   +1 more source

THE ACCIDENTS OF VACCINATION. [PDF]

, 1898
T. Colcott Fox
openalex   +1 more source

Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance

Advanced Materials, EarlyView.
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee, Heung Jin Jeon, Dohyub Jang, Deukhee Lee, Solbi Kim, Minju Han, Sharon Jiyoon Jung, Jung‐Hyun Lee, Jia Choi, Dong Ha Kim, Dong June Ahn, Keri Kim, Sehoon Kim, Hyo‐Jin Lee, SeungBeum Suh   +14 more
wiley   +1 more source

Design and Analysis of Novel HEV Vaccine Variants and Evaluation of Two Selected Candidates in a Porcine Infection Model. [PDF]

Liver Int
Hrabal I, Aliabadi E, Weber S, Ssebyatika GL, Krey T, Holicki CM, Schmid L, Dinkelborg K, Schröder C, Fast C, Behrendt P, Groschup MH, Eiden M.   +12 more
europepmc   +1 more source